Pre-analytical variables have the potential to significantly impact proteomic profiles. Furthermore, the annotations provided for the TCGA tumors do not include relevant information on such pre-analytical variables. To eliminate potential artifacts resulting from pre-analytic variables, a prosperctive collection of tumor, adjacent normal tissue, and blood from each of three tumor types, braest cancer, ovarian cancer and colon cancer, will be commenced. These collections will be performed under strict adherence to SOPs designed to minimize and standardize the effects of post-acquisition pre-analytical variableson proteomic profiles.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research and Development Contracts (N01)
Project #
261200800001E-51-0-102
Application #
8569501
Study Section
Project Start
2008-09-26
Project End
2018-09-25
Budget Start
Budget End
Support Year
Fiscal Year
2012
Total Cost
$2,000,000
Indirect Cost
Name
Saic-Frederick, Inc.
Department
Type
DUNS #
159990456
City
Frederick
State
MD
Country
United States
Zip Code
21702