Optimize formulations of topical Itraconazole for absorption by human skin;Test GLP grade formulation on a human BCC model grafted on nude mice. Test GLP grade Itraconazole creams (the 2-3 best candidates from #1 above) vs. placebo on the prevention of actual BCC tumors in Ptch1+/-K14-Cre-ER P53 fl/fl mice.

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
261201200018I-0-26100005-1
Application #
8739518
Study Section
Project Start
2013-09-18
Project End
2015-09-17
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$608,798
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065