This contract performs in vitro confirmatory testing of drug substances submitted to DAIDS for further development as potential anti-HIV therapies. The goal is to independently confirm the initial observation of anti-HIV activity of promising drug substances and then examine the spectrum of in vitro activity in multiple cell types against panels of laboratory and/or primary HIV isolates representing viruses with different co-receptor usage, clade classification, and/or drug sensitivity. In addition, potential drug-drug interactions shall be examined and drug-resistant HIV isolates shall be made for the most promising drug substances.

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
272200700041C-8-0-1
Application #
8730038
Study Section
Project Start
2013-09-30
Project End
2014-09-29
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$431,029
Indirect Cost
Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205