The goals of the Innate Immune Receptors and Adjuvant Discovery program are to discover, characterize, and support preclinical testing of new adjuvant candidates based upon triggering of the human innate immune system. Adjuvants are defined as molecules that act via innate immune receptors to activate beneficial innate and/or adaptive (T and B cell-mediated) immune responses. Using high throughput screening techniques, investigators will screen compound libraries to identify potential adjuvant products that may be developed as components of antigen specific vaccines against infectious disease, or may serve as stand-alone agents that transiently prevent or treat infectious disease.

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
272200900031C-3-0-1
Application #
8750996
Study Section
Project Start
2009-09-30
Project End
2014-09-29
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$1,843,979
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109