Immunological aging or Immunosenescence and the mechanisms that accelerate it, such as radiation, reduce the host's capability to mount a robust immune response, thus increasing the host's susceptibility to infectious agents and a variety of malignant and non-malignant diseases The Studies of Immunosenescence and Other Late Effects of Acute Radiation Exposure in Atomic Bomb Survivors program supports research into how the late effects of acute radiation exposure and aging affect the process of immunosenescence. The results of the proposed studies on this unique aging population will not only provide a wealth of fundamental biological information on the process of and the impact of radiation on the aging of the immune system, but may also provide insights that lead to amelioration of immune function and other health outcomes in radiation-exposed older adults.

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
272200900059C-5-0-1
Application #
8740455
Study Section
Project Start
2009-09-30
Project End
2015-09-29
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$410,677
Indirect Cost
Name
Radiation Effects Researc
Department
Type
DUNS #
704549278
City
Hiroshima
State
Country
Japan
Zip Code
732-0-815