This project addresses key regulatory considerations relevant to using bacteriophages for decolonization of the drug-resistant nosocomial pathogens, VRE and MRSA. These include characterizing pathogen resistance to phage, defining phage mixtures (cocktails) to circumvent resistance, optimizing mouse models to evaluate pathogen decolonization and identifying endpoints that support claims for clinical benefit (e.g., reduced risk of disease transmission).

Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
2017
Total Cost
Indirect Cost
City
State
Country
Zip Code