The Brown/Tufts University Fogarty AIDS International Research Training Program (D43TW000237) is applying for continued support of its educational activities for the next 5 years, 2010-2015. Over the past 16 years, the Brown/Tufts Fogarty AIDS International Training and Research Program (AITRP) has trained over 100 clinical investigators from India, the Philippines, Cambodia, Indonesia, and, most recently, western Kenya, resulting in about 100 peer-reviewed publications over the past 5 years alone. Brown/Tufts AITRP trainees have assumed national leadership positions in each of these countries, and several play significant roles in multinational clinical research networks. In this new cycle the Brown/Tufts AITRP proposes to focus on longer term training, advanced degree training at either Brown or Tufts. Trainees may elect to participate in MPH, Masters Programs in Biostatistics, or Clinical Research, as well as PhD programs. In addition, we have developed one year, post doctoral mentored research training courses in a variety of clinical research disciplines, including Molecular Virology, Clinical Trial Research Design, HIV Prevention Research, Women's Health, Nutrition and Metabolic Studies, as well as Pharmacology. In order to identify the highest caliber trainees, the AITRP has developed a formal advisory process, which includes the Directors of several international AIDS programs, Public Health Research Institutes and Research Universities each of the affiliated countries. In addition, a formal mentoring program has been developed which will ensure that each international trainee is in frequent contact with a designated Brown or Tufts faculty mentor whose research interests are congruent with those of the relevant trainee. Prospective candidates will be proposed by our international advisors and their selection with be conducted during the monthly meetings of the Brown-Tufts Fogarty AITRP Executive Committee, which includes accomplished faculty from all affiliated institutions with diverse academic training and a commitment to international public health training, followed by approval and guidance from the Training Advisory Group. The University of Ghana is being added as a pilot training site.

National Institute of Health (NIH)
Fogarty International Center (FIC)
International Research Training Grants (D43)
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Special Emphasis Panel (ZRG1-ICP2-B (52))
Program Officer
Mcdermott, Jeanne
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Brown University
Obstetrics & Gynecology
Schools of Medicine
United States
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Archampong, Timothy Na; Boyce, Ceejay L; Lartey, Margaret et al. (2016) HBV genotypes and drug resistance mutations in antiretroviral treatment-naive and treatment-experienced HBV-HIV-coinfected patients. Antivir Ther :
Sau, Mealiny Sokun; Balamane, Maya; Lurie, Mark et al. (2016) Assessment of Prevention of Mother-to-Child Transmission HIV Services in the Bantey Meanchey Province in Cambodia. J Int Assoc Provid AIDS Care 15:345-9
Archampong, Timothy N A; Lartey, Margaret; Sagoe, Kwamena W et al. (2016) Proportion and factors associated with Hepatitis B viremia in antiretroviral treatment naïve and experienced HIV co-infected Ghanaian patients. BMC Infect Dis 16:14
Awortwe, Charles; Manda, Vamshi K; Avonto, Cristina et al. (2015) In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities. Drug Metab Lett 9:48-62
Thuppal, Sowmyanarayanan V; Wanke, Christine A; Noubary, Farzad et al. (2015) Toxicity and clinical outcomes in patients with HIV on zidovudine and tenofovir based regimens: a retrospective cohort study. Trans R Soc Trop Med Hyg 109:379-85
Awortwe, Charles; Manda, Vamshi K; Avonto, Cristina et al. (2015) Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway. Xenobiotica 45:218-29
Awortwe, Charles; Bouic, Patrick J; Masimirembwa, Collen M et al. (2014) Inhibition of major drug metabolizing CYPs by common herbal medicines used by HIV/AIDS patients in Africa-- implications for herb-drug interactions. Drug Metab Lett 7:83-95
Awortwe, Charles; Fasinu, P S; Rosenkranz, B (2014) Application of Caco-2 cell line in herb-drug interaction studies: current approaches and challenges. J Pharm Pharm Sci 17:1-19
McMahon, James H; Manoharan, Anand; Wanke, Christine A et al. (2013) Pharmacy and self-report adherence measures to predict virological outcomes for patients on free antiretroviral therapy in Tamil Nadu, India. AIDS Behav 17:2253-9
Padmapriyadarsini, C; Bhavani, P K; Tang, Alice et al. (2013) Early changes in hepatic function among HIV-tuberculosis patients treated with nevirapine or efavirenz along with rifampin-based anti-tuberculosis therapy. Int J Infect Dis 17:e1154-9

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