This is a competing renewal application for a Fogarty International Center-sponsored Global Infectious Disease Research Training Program in vaccine development and public health between the International Centre for Diarrhoeal Research in Dhaka, Bangladesh (ICDDR,B) and the Massachusetts General Hospital (MGH) in Boston, Massachusetts. Now in its 10th year, this training program has focused on long-term training of young investigators at the ICDDR,B. In this renewal application, we propose to focus on in-country training in Bangladesh, to include training tracks in both laboratory sciences and public health investigation, and to include trainees at a range of career development stages. The research platform upon which training would occur is based upon active and successful NIH and other collaborative projects between the co-program directors for this training program, Dr. Firdausi Qadri, Head of the Immunology Unit in the Laboratory Science Division at the ICDDR,B, and Dr. Edward Ryan, Division of Infectious Diseases, Massachusetts General Hospital. These co-program directors collaborate closely on a number of research projects, including a NIAID-sponsored International Collaborations in Infectious Disease Research (ICIDR) award focusing on evaluating protective immunity during cholera, and a NIAID-sponsored U01 project appplying high throughput technologies to Vibrio cholerae infection and vaccine development. We propose to train individuals through both degree and non-degree programs, the former through collaborative arrangements with the James P. Grant School of Public Health-BRAC University in Dhaka, Bangladesh (Masters of Public Health Program), and in focused laboratory research to support Masters of Science and Ph.D. degree candidacy in Biochemistry and Molecular Biology, Dhaka University. We also propose to include long-term non-degree granting training, including post- masters (in Dhaka and Boston) and post-doctoral fellowship training (in Dhaka). We have assembled faculty with expertise in laboratory sciences, infectious diseases and public health, and the goal of this program would be to meet research and public health needs at the ICDDR,B through individual and institutional capacity building.
This is a competing renewal application for a Fogarty International Center-sponsored Global Infectious Disease Research Training Program in vaccine development and public health between the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B), and the Massachusetts General Hospital (MGH) in Boston. The program would focus on long-term training in laboratory sciences and public health, would include both degree and non-degree programs, and would provide individual and institutional capacity building at the ICDDR,B. The program would build upon ongoing and active scientific collaborations between the ICDDR,B and MGH on Vibrio cholerae, enteric infection, and vaccine development and evaluation.
|Uddin, Taher; Aktar, Amena; Xu, Peng et al. (2014) Immune responses to O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 Ogawa in adult Bangladeshi recipients of an oral killed cholera vaccine and comparison to responses in patients with cholera. Am J Trop Med Hyg 90:873-81|
|Weil, Ana A; Begum, Yasmin; Chowdhury, Fahima et al. (2014) Bacterial shedding in household contacts of cholera patients in Dhaka, Bangladesh. Am J Trop Med Hyg 91:738-42|
|Alam, Mohammad Murshid; Bufano, Megan Kelly; Xu, Peng et al. (2014) Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide. PLoS Negl Trop Dis 8:e2683|
|Bhuiyan, Saruar; Sayeed, Abu; Khanam, Farhana et al. (2014) Cellular and cytokine responses to Salmonella enterica serotype Typhi proteins in patients with typhoid fever in Bangladesh. Am J Trop Med Hyg 90:1024-30|
|Charles, Richelle C; Liang, Li; Khanam, Farhana et al. (2014) Immunoproteomic analysis of antibody in lymphocyte supernatant in patients with typhoid fever in Bangladesh. Clin Vaccine Immunol 21:280-5|
|Alam, Mohammad Murshid; Aktar, Amena; Afrin, Sadia et al. (2014) Antigen-specific memory B-cell responses to enterotoxigenic Escherichia coli infection in Bangladeshi adults. PLoS Negl Trop Dis 8:e2822|
|Sugimoto, Jonathan D; Koepke, Amanda A; Kenah, Eben E et al. (2014) Household Transmission of Vibrio cholerae in Bangladesh. PLoS Negl Trop Dis 8:e3314|
|Charles, Richelle C; Sultana, Tania; Alam, Mohammad Murshid et al. (2013) Identification of immunogenic Salmonella enterica serotype Typhi antigens expressed in chronic biliary carriers of S. Typhi in Kathmandu, Nepal. PLoS Negl Trop Dis 7:e2335|
|Alam, Mohammad Murshid; Leung, Daniel T; Akhtar, Marjahan et al. (2013) Antibody avidity in humoral immune responses in Bangladeshi children and adults following administration of an oral killed cholera vaccine. Clin Vaccine Immunol 20:1541-8|
|Khanam, Farhana; Sheikh, Alaullah; Sayeed, Md Abu et al. (2013) Evaluation of a typhoid/paratyphoid diagnostic assay (TPTest) detecting anti-Salmonella IgA in secretions of peripheral blood lymphocytes in patients in Dhaka, Bangladesh. PLoS Negl Trop Dis 7:e2316|
Showing the most recent 10 out of 53 publications