The overall objective of our Fogarty Training Program is to increase research capacity to identify and evaluate strategies to interrupt the transmission and pathogenesis of leishmaniasis and other vector-borne diseases endemic in Colombia (Dengue and Malaria). With the aim of building long-term sustainable capacity to address national and regional research needs, the parent grant has enabled Yale and CIDEIM to develop and deliver a series of live learning post-graduate courses on topics relevant to vector-borne prevention, treatment and control that are not sufficiently covered in traditional graduate and post-graduate academic curricula. At the same time, there is a critical need for strengthening core research skills which can be applied to the development, planning, implementation, evaluation and subsequent writing of research on any infectious disease or public health issue. The general aim of this application is to build institutional capacity in CIDEIM to develop and use virtual e-learning methodologies to develop virtual training programs focused on health research management skills and access to information. More specifically, this application is to: (1) develop an appropriate, user-friendly, interactive online version of the "Effective Project Planning and Evaluation for Health Research" (EPPE) training program;(2) develop an online training program in Access to Scientific Literature;(3) transfer an existing Biostatistics course taught at CIDEIM to a fully online format;(4) offer these new virtual courses through the CIDEIM website and explore other avenues to make these courses widely available to health students, researchers and practitioners.

Public Health Relevance

The activities outlined above will ensure the developnnent of expertise in the creation, implementation and dissemination of online curricula, and the application of the same to virtual training programs to strengthen core health research skills. Virtual modalities will facilitate the integration of this training into higher education curricula and provide flexible continuing education possibilities for health researchers and practitioners.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW006589-10S1
Application #
8733341
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (51))
Program Officer
Sina, Barbara J
Project Start
2003-09-01
Project End
2014-03-31
Budget Start
2013-09-20
Budget End
2014-03-31
Support Year
10
Fiscal Year
2013
Total Cost
$48,182
Indirect Cost
Name
Yale University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Gomez, Maria Adelaida; Navas, Adriana; Marquez, Ricardo et al. (2014) Leishmania panamensis infection and antimonial drugs modulate expression of macrophage drug transporters and metabolizing enzymes: impact on intracellular parasite survival. J Antimicrob Chemother 69:139-49
Rodriguez-Pinto, Daniel; Saravia, Nancy Gore; McMahon-Pratt, Diane (2014) CD4 T cell activation by B cells in human Leishmania (Viannia) infection. BMC Infect Dis 14:108
Obonaga, Ricardo; Fernandez, Olga Lucia; Valderrama, Liliana et al. (2014) Treatment failure and miltefosine susceptibility in dermal leishmaniasis caused by Leishmania subgenus Viannia species. Antimicrob Agents Chemother 58:144-52
Fernández, Olga Lucía; Diaz-Toro, Yira; Ovalle, Clemencia et al. (2014) Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia. PLoS Negl Trop Dis 8:e2871
Navas, Adriana; Vargas, Deninson Alejandro; Freudzon, Marina et al. (2014) Chronicity of dermal leishmaniasis caused by Leishmania panamensis is associated with parasite-mediated induction of chemokine gene expression. Infect Immun 82:2872-80
Aksoy, Serap; Caccone, Adalgisa; Galvani, Alison P et al. (2013) Glossina fuscipes populations provide insights for human African trypanosomiasis transmission in Uganda. Trends Parasitol 29:394-406
Rodriguez-Pinto, Daniel; Navas, Adriana; Blanco, Victor Manuel et al. (2012) Regulatory T cells in the pathogenesis and healing of chronic human dermal leishmaniasis caused by Leishmania (Viannia) species. PLoS Negl Trop Dis 6:e1627
Rubiano, Luisa Consuelo; Miranda, María Consuelo; Muvdi Arenas, Sandra et al. (2012) Noninferiority of miltefosine versus meglumine antimoniate for cutaneous leishmaniasis in children. J Infect Dis 205:684-92
Gallego, Carolina; Golenbock, Douglas; Gomez, Maria Adelaida et al. (2011) Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis. Infect Immun 79:2871-9
Ferro, Cristina; Marín, Dairo; Góngora, Rafael et al. (2011) Phlebotomine vector ecology in the domestic transmission of American cutaneous leishmaniasis in Chaparral, Colombia. Am J Trop Med Hyg 85:847-56

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