The overall goal of this project is to enhance research and training activities in enteric infectious disease at the Christian Medical College, Vellore through an application for a Global Infectious Disease Research and Training program from the Fogarty International Center.
We aim to establish training in enteric infectious diseases-related research, based on a longstanding and ongoing collaborative partnership between investigators at Tufts-New England Medical Center (T-NEMC)/Tufts University School of Medicine (TUSM) and our institution, Christian Medical College (CMC) Hospital, Vellore, India, which has a strong independent and collaborative medical research program. Enteric infectious diseases continue to be a major cause of morbidity and mortality in India, and the goal of our collaborative research is to better understand, investigate, control and prevent diarrheal disease in south India. The project specifically aims to train scientists from southern India in a variety of disciplines necessary to identify and investigate gastrointestinal infections, to extend and reinforce research and training activities in enteric infectious disease at CMC, thereby developing and strengthening CMC as a regional center of excellence for enteric infectious disease research training.
These specific aims will be accomplished by implementation of a multidisciplinary, needs-based research and training program which will train junior and mid-level faculty from India for periods from 6 weeks to 6 months, and towards formal degrees. Research projects will be developed and conducted by the returning trainees, under the mentorship of program faculty. Centers of excellence will be developed in multiple disciplines to support and complement enteric infectious disease research in southern India, building on the knowledge and skills of returning trainees. Complementation of research will be promoted through the establishment of a trainee and faculty network and multi-disciplinary discussion group. In-country workshops will be conducted by program faculty and returning trainees, at which additional Indian researchers and public health care workers will be trained. The development of centers of excellence in enteric infectious diseases research will increase global infrastructure and capacity for dealing with endemic and emerging enteric infectious diseases. The faculty and trainees will translate into public health practice in India, the results of the research carried out as a result of this and other collaborative research projects.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW007392-04
Application #
7392764
Study Section
Special Emphasis Panel (ZRG1-ICP-2 (91))
Program Officer
Sina, Barbara J
Project Start
2005-08-15
Project End
2010-03-31
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
4
Fiscal Year
2008
Total Cost
$141,717
Indirect Cost
Name
Christian Medical College
Department
Type
DUNS #
918483710
City
Vellore
State
Country
India
Zip Code
63200-2
Rogawski, Elizabeth T; Meshnick, Steven R; Becker-Dreps, Sylvia et al. (2016) Reduction in diarrhoeal rates through interventions that prevent unnecessary antibiotic exposure early in life in an observational birth cohort. J Epidemiol Community Health 70:500-5
Grassly, Nicholas C; Praharaj, Ira; Babji, Sudhir et al. (2016) The effect of azithromycin on the immunogenicity of oral poliovirus vaccine: a double-blind randomised placebo-controlled trial in seronegative Indian infants. Lancet Infect Dis 16:905-14
Dinh, Duy M; Ramadass, Balamurugan; Kattula, Deepthi et al. (2016) Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India. PLoS One 11:e0155405
Rogawski, Elizabeth T; Westreich, Daniel J; Becker-Dreps, Sylvia et al. (2015) Antibiotic treatment of diarrhoea is associated with decreased time to the next diarrhoea episode among young children in Vellore, India. Int J Epidemiol 44:978-87
Thomas, Rahul Jacob; Ramanujam, Karthikeyan; Velusamy, Vasanthakumar et al. (2015) Comparison of fieldworker interview and a pictorial diary method for recording morbidity of infants in semi-urban slums. BMC Public Health 15:43
Mohan, Venkata Raghava; Sarkar, Rajiv; Abraham, Vinod Joseph et al. (2015) Differential patterns, trends and hotspots of road traffic injuries on different road networks in Vellore district, southern India. Trop Med Int Health 20:293-303
Rogawski, Elizabeth T; Westreich, Daniel; Becker-Dreps, Sylvia et al. (2015) The effect of early life antibiotic exposures on diarrheal rates among young children in Vellore, India. Pediatr Infect Dis J 34:583-8
Kattula, D; Francis, M R; Kulinkina, A et al. (2015) Environmental predictors of diarrhoeal infection for rural and urban communities in south India in children and adults. Epidemiol Infect 143:3036-47
Rogawski, Elizabeth T; Westreich, Daniel J; Adair, Linda S et al. (2015) Early Life Antibiotic Exposure Is Not Associated with Growth in Young Children of Vellore, India. J Pediatr 167:1096-102.e3
Sarkar, Rajiv; Kattula, Deepthi; Francis, Mark R et al. (2014) Risk factors for cryptosporidiosis among children in a semi urban slum in southern India: a nested case-control study. Am J Trop Med Hyg 91:1128-37

Showing the most recent 10 out of 44 publications