Responding to Tanzanian national priorities for optimizing the care of persons living with HIV infection, Duke University and the Kilimanjaro Christian Medical Centre (KCMC) will develop a Sociobehavioral Sciences (SBS) Research Core at KCMC focused on HIV/AIDS care. SBS research skills are essential for understanding critical issues relating to HIV testing, stigma, linkage and retention in care, treatment adherence and co-morbidities such as mental illness and substance abuse, which relate strongly to clinical outcomes. The acquisition of these research skills will occur through South-South training opportunities with the University of Cape Town (UCT), and North-South opportunities with Duke. Given the goal of research independence and creation of a regional training facility for the Team by April 2018, we have developed a careful plan for Team composition which emphasizes robust and complementary SBS research skills. Four candidates will begin PhD training in year 1, pursuing expertise in epidemiology/public health, health promotion/behavior, and psychology. Two trainees will also begin Masters' in Medicine training in Psychiatry in year 1. In subsequent years additional Team members will initiate medium- and short-term training to develop expertise in public health aspects of mental illness, point of care diagnostics, nursing, data management and research administration. Strong mentorship will be offered by faculty at Duke and UCT through their expertise and funded research in SBS aspects of HIV infection. The trainees' research will expand existing collaborative research efforts with Duke and develop new collaborations with UCT under the leadership of the newly developed KCMC SBS Research Core Team. Program administration will build upon the past training successes of the KCMC-Duke collaboration, and future success will be ensured through careful communication, rigorous monitoring and evaluation, and accountability to the Training Advisory Committee and an External Advisory Committee.

Public Health Relevance

The proposed training program will create a Sociobehavioral Sciences Research Core Team at the Kilimanjaro Christian Medical Centre in Moshi, Tanzania through a carefully selected portfolio of training opportunities. This Team will study HIV voluntary counseling and testing, linkage and retention in care, adherence to medications, and co- morbidities of mental illness and substance abuse. The knowledge gained from this research will improve public health by informing health care providers and policymakers about best practices in the management of persons living with HIV infection.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
3D43TW009595-04S1
Application #
9296481
Study Section
Program Officer
Mcdermott, Jeanne
Project Start
2013-08-01
Project End
2018-01-31
Budget Start
2016-02-01
Budget End
2017-01-31
Support Year
4
Fiscal Year
2016
Total Cost
$101,234
Indirect Cost
$1,234
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Knettel, Brandon A; Cichowitz, Cody; Ngocho, James Samwel et al. (2018) Retention in HIV Care During Pregnancy and the Postpartum Period in the Option B+ Era: Systematic Review and Meta-Analysis of Studies in Africa. J Acquir Immune Defic Syndr 77:427-438
Cichowitz, Cody; Mazuguni, Festo; Minja, Linda et al. (2018) Vulnerable at Each Step in the PMTCT Care Cascade: High Loss to Follow Up During Pregnancy and the Postpartum Period in Tanzania. AIDS Behav :
Ramadhani, Habib O; Muiruri, Charles; Maro, Venance P et al. (2018) Patient-Initiated Repackaging of Antiretroviral Therapy, Viral Suppression and Drug Resistance. AIDS Behav 22:1671-1678
Watt, Melissa H; Cichowitz, Cody; Kisigo, Godfrey et al. (2018) Predictors of postpartum HIV care engagement for women enrolled in prevention of mother-to-child transmission (PMTCT) programs in Tanzania. AIDS Care :1-12
Damian, Damian J; Njau, Bernard; Lisasi, Ester et al. (2017) Trends in maternal and neonatal mortality in South Africa: a systematic review protocol. Syst Rev 6:165
Rubach, Matthew P; Maro, Venance P; Bartlett, John A et al. (2015) Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy. Am J Trop Med Hyg 92:454-62
Harmon, James L; Collins-Ogle, Michelle; Bartlett, John A et al. (2014) Integrating routine HIV screening into a primary care setting in rural North Carolina. J Assoc Nurses AIDS Care 25:70-82
Nyindo, Mramba; Kitau, Jovin; Lisasi, Esther et al. (2014) Introduction of team-based learning (TBL) at Kilimanjaro Christian Medical University College: experience with the ectoparasites module. Med Teach 36:308-13
Lisasi, Esther; Kulanga, Ahaz; Muiruri, Charles et al. (2014) Modernizing and transforming medical education at the Kilimanjaro Christian Medical University College. Acad Med 89:S60-4