Sleep loss is a common consequence of medical and psychological illness, as well as life style conditions (e.g., sleep restriction from shift work, jet lag, etc.), but its impact on affect has not been established. This study therefore aims to test the effects of sleep deprivation on behavioral and physiological manifestations of affective responses to emotion probes and performance stressors. It will also seek to identify neurobehavioral, psychological and demographic correlates of these responses. Healthy adult volunteers will spend two days in a laboratory facility. Subjects will be randomly assigned to either a sleep deprivation or control condition. On both days of the study, subjects' physiological and behavioral responses to emotion probes and psychosocial stressors will be measured. The hypothesis that sleep deprivation influences affect regulation will be tested using mixed model repeated measures ANOVA. Subjects' psychological and neurocognitive function will also be evaluated using validated tests and procedures. Relationships among these variables and affective responses will be tested using regression techniques. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31MH079604-02
Application #
7301331
Study Section
Special Emphasis Panel (ZRG1-F11-B (20))
Program Officer
Rubio, Mercedes
Project Start
2006-09-30
Project End
2009-09-29
Budget Start
2007-09-30
Budget End
2008-09-29
Support Year
2
Fiscal Year
2007
Total Cost
$39,262
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Minkel, Jared; Moreta, Marisa; Muto, Julianne et al. (2014) Sleep deprivation potentiates HPA axis stress reactivity in healthy adults. Health Psychol 33:1430-4
Minkel, Jared D; Banks, Siobhan; Htaik, Oo et al. (2012) Sleep deprivation and stressors: evidence for elevated negative affect in response to mild stressors when sleep deprived. Emotion 12:1015-20
Minkel, Jared; Htaik, Oo; Banks, Siobhan et al. (2011) Emotional expressiveness in sleep-deprived healthy adults. Behav Sleep Med 9:5-14