Co-morbid PTSD and alcohol use disorders are both common and debilitating, therefore, identification of factors related to their development is of great import. Research findings support a self-medication hypothesis to explain this comorbidity. Yet mechanisms explaining the use of alcohol for self-medication of PTSD remain unaddressed. The overarching purpose of this study is to examine a cognitive model of AUD following traumatic events. This model will integrate cognitive processing theory of PTSD with models for the development of AUD emphasizing cognitive expectancies. This study will use a longitudinal design, assessing 100 adult women with a physical or sexual assault one, three, and six months after the traumatic event to determine how AUD develop over time, as a function of general and PTSD-specific alcohol outcome expectancies, cognitions affected by the traumatic event, and severity of PTSD symptoms.
Aim 1 : Examine general alcohol expectancies 1 month post-trauma, as predictors of alcohol consumption, and PTSD-specific alcohol expectancies 3 months post-trauma.
Aim 2 : Examine PTSD severity I month post-trauma, as a predictor of alcohol consumption and PTSD-specific alcohol expectancies 3 months post-trauma.
Aim 3 : Evaluate assimilation and over-accommodation I month post-trauma as predictors of PTSD symptoms 3 months post-trauma.
Aim 4 : Evaluate alcohol consumption, PTSD-specific alcohol expectancies, and PTSD severity 3 months post-trauma as predictors of alcohol use disorders 6 months post-trauma.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32AA014728-02
Application #
6830778
Study Section
Special Emphasis Panel (ZAA1-EE (22))
Program Officer
Grandison, Lindsey
Project Start
2004-01-01
Project End
2006-12-31
Budget Start
2005-01-01
Budget End
2005-12-31
Support Year
2
Fiscal Year
2005
Total Cost
$45,532
Indirect Cost
Name
University of Washington
Department
Psychiatry
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Kaysen, Debra; Atkins, David C; Moore, Sally A et al. (2011) Alcohol Use, Problems, and the Course of Posttraumatic Stress Disorder: A Prospective Study of Female Crime Victims. J Dual Diagn 7:262-279
Kaysen, Debra; Rosen, Gerald; Bowman, Marilyn et al. (2010) Duration of exposure and the dose-response model of PTSD. J Interpers Violence 25:63-74
Kaysen, Debra L; Lindgren, Kristen P; Lee, Christine M et al. (2010) Alcohol-involved assault and the course of PTSD in female crime victims. J Trauma Stress 23:523-7
Nguyen, Hong V; Kaysen, Debra; Dillworth, Tiara M et al. (2010) Incapacitated rape and alcohol use in White and Asian American college women. Violence Against Women 16:919-33
Kaysen, Debra; Pantalone, David W; Chawla, Neharika et al. (2008) Posttraumatic stress disorder, alcohol use, and physical health concerns. J Behav Med 31:115-25
Kaysen, Debra; Dillworth, Tiara M; Simpson, Tracy et al. (2007) Domestic violence and alcohol use: trauma-related symptoms and motives for drinking. Addict Behav 32:1272-83
Kaysen, Debra; Neighbors, Clayton; Martell, Joel et al. (2006) Incapacitated rape and alcohol use: a prospective analysis. Addict Behav 31:1820-32
Kaysen, Debra; Simpson, Tracy; Dillworth, Tiara et al. (2006) Alcohol problems and posttraumatic stress disorder in female crime victims. J Trauma Stress 19:399-403
Kaysen, Debra; Scher, Christine D; Mastnak, Julie et al. (2005) Cognitive mediation of childhood maltreatment and adult depression in recent crime victims. Behav Ther 36:235-44
Kaysen, Debra; Morris, Miranda K; Rizvi, Shireen L et al. (2005) Peritraumatic responses and their relationship to perceptions of threat in female crime victims. Violence Against Women 11:1515-35

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