Humans can recognize a familiar object even though it dramatically changes appearance as it is viewed from different angles, distances, and lighting conditions.
The aim of the proposed research is to use fMRI to directly examine object representations in visual cortex that support invariant object recognition in humans. Changes in neural activity will be measured with respect to several object transformations such as changes in object size, orientation, and illumination direction. Most importantly, the degree of change will be varied parametrically in order to describe the neural tuning (i.e., sensitivity) of each area to a particular transformation. Unlike previous studies, this methodology provides for a precise determination of the degree to which a visual area is invariant to a particular transformation. In addition, changes in the neural tuning functions when participants attend to a transformation compared to when they do not, will reveal both the degree and manner of top-down modulation. Taken together, these findings would provide for a comprehensive understanding of the function and organization of visual cortical areas involved in invariant object recognition. In addition, the findings would be of critical importance for understanding the impact of neurological damage depending upon the representations within the underlying cortical area.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32EY015045-01
Application #
6694252
Study Section
Special Emphasis Panel (ZRG1-F02B (20))
Program Officer
Oberdorfer, Michael
Project Start
2003-09-30
Project End
2005-09-29
Budget Start
2003-09-30
Budget End
2004-09-29
Support Year
1
Fiscal Year
2003
Total Cost
$41,608
Indirect Cost
Name
Stanford University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Andresen, David R; Vinberg, Joakim; Grill-Spector, Kalanit (2009) The representation of object viewpoint in human visual cortex. Neuroimage 45:522-36