This study will test the hypotheses that individuals with chronic stroke who participate in treadmill (TM) exercise 3x/wk for 6 months will improve cardiovascular fitness, balance, and ambulatory function, which will be associated with increased ambulatory activity, reduced subjective fatigue, improved falls efficacy, higher social participation, and better reported quality of life than individuals with usual care. A sample of 18 community-dwelling men and women with chronic stroke complete baseline testing, then enroll in a delayed- entry cohort. Functional mobility testing includes self-selected floor-walking velocity, 6-minute timed walks, analysis of gait, Berg Balance Scale, and step activity monitoring. Fitness measures include VO2 peak and economy of gait. Social/behavioral measures are the Fatigue Severity Scale, Falls Efficacy Scale, MOS-SF-36 Questionnaire, and an individual structured interview about social participation. After the 6-month run-in, participants exercise on TM three times a week in the Baltimore VA Senior Exercise Rehabilitation Center. Each participant receives an individualized exercise prescription, with progression of exercise intensity and duration. All baseline measures are repeated upon completion of 3 and 6 months of TM exercise training. Data are analyzed to determine whether TM exercise affects fitness, mobility and real-world ambulatory activity, and whether TM exercise impacts fatigue, falls efficacy, social participation, or quality of life. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32NR010058-02
Application #
7285200
Study Section
National Institute of Nursing Research Initial Review Group (NRRC)
Program Officer
Mann Koepke, Kathy M
Project Start
2006-07-14
Project End
2009-07-13
Budget Start
2007-07-26
Budget End
2008-07-13
Support Year
2
Fiscal Year
2007
Total Cost
$51,286
Indirect Cost
Name
University of Maryland Baltimore
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Michael, Kathleen; Goldberg, Andrew P; Treuth, Margarita S et al. (2009) Progressive adaptive physical activity in stroke improves balance, gait, and fitness: preliminary results. Top Stroke Rehabil 16:133-9
Resnick, Barbara; Michael, Kathleen; Shaughnessy, Marianne et al. (2008) Motivators for treadmill exercise after stroke. Top Stroke Rehabil 15:494-502
Michael, Kathleen; Macko, Richard F (2007) Ambulatory activity intensity profiles, fitness, and fatigue in chronic stroke. Top Stroke Rehabil 14:5-12