The principal goal of this project is to conduct a cross-sectional social epidemiologic and behavioral research study for the purposes of characterizing different risk factors associated with HIV infection acquisition and transmission among impoverished, Hispanic women in Puerto Rico living in public housing. The general hypothesis behind the proposed research is that risk of HIV acquisition and transmission for these women is exacerbated by various individual, social and environmental factors unique to the public housing environment and in order to decrease HIV risk, these factors must be identified and measured. 1. Measure HIV/STI prevalence and incidence among women living in public housing developments (PHDs) in Ponce, Puerto Rico (PR). 2. Identify individual, social, and environmental factors contributing to increased HIV/STI risk for Hispanic women living in PHDs in Ponce, PR. 3. Determine the feasibility of an HIV prevention intervention targeting Hispanic women living in PHDs in Ponce, PR. The significance of the proposed research will enhance knowledge and understanding of multilevel factors that influence HIV/STI risk behaviors as well as the consequences and differences in HIV-associated risks among impoverished women Latina women living in public housing in Puerto Rico. Qualitative and quantitative social epidemiological and behavioral sciences approaches will be used to target impoverished women living in PHDs. By including women from this population, comparisons of HIV/STI risk factors and outcomes can be made, providing a much needed picture of the scope of risks for impoverished women in Puerto Rico and how prevention messages and programs will need to be tailored.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12MD007579-28
Application #
8573389
Study Section
Special Emphasis Panel (ZRR1-RI-1)
Project Start
2013-01-01
Project End
2014-12-31
Budget Start
2013-01-01
Budget End
2013-12-31
Support Year
28
Fiscal Year
2013
Total Cost
$269,305
Indirect Cost
$96,767
Name
Ponce School of Medicine
Department
Type
DUNS #
105742043
City
Ponce
State
PR
Country
United States
Zip Code
00732
Rivera-Rivera, Yainyrette; Vázquez-Santiago, Fabián J; Albino, Elinette et al. (2016) Impact of Depression and Inflammation on the Progression of HIV Disease. J Clin Cell Immunol 7:
Hou, Wangheng; Torres, Lilith; Cruz-Cosme, Ruth et al. (2016) Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus. J Virol 90:7339-49
de Jesus, Edelmarie Rivera; Isidro, Raymond A; Cruz, Myrella L et al. (2016) Adoptive Transfer of Dendritic Cells Expressing Fas Ligand Modulates Intestinal Inflammation in a Model of Inflammatory Bowel Disease. J Clin Cell Immunol 7:
López, Pablo; Rivera-Amill, Vanessa; Rodríguez, Nayra et al. (2016) The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico. Int J Environ Res Public Health 13:ijerph13010055
Ortiz, Carmen; Morales, Luisa; Sastre, Miguel et al. (2016) Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A. Evid Based Complement Alternat Med 2016:3696232
Ortiz, Maricelly Santiago; Forti, Kevin Muñoz; Suárez Martinez, Edu B et al. (2016) Effects of Antioxidant N-acetylcysteine Against Paraquat-Induced Oxidative Stress in Vital Tissues of Mice. Int J Sci Basic Appl Res 26:26-46
Noel, Richard J; Kaul, Marcus (2016) The 22nd Scientific Conference of the Society on Neuroimmune Pharmacology. J Neuroimmune Pharmacol 11 Suppl 1:S1-2
Torres-Reverón, Annelyn; Palermo, Karylane; Hernández-López, Anixa et al. (2016) Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray. Reprod Sci 23:1158-67
Quiñones, María M; Maldonado, Lizette; Velazquez, Bethzaly et al. (2016) Candesartan ameliorates impaired fear extinction induced by innate immune activation. Brain Behav Immun 52:169-77
Abreu-Delgado, Yamilka; Isidro, Raymond A; Torres, Esther A et al. (2016) Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease. World J Gastroenterol 22:3581-91

Showing the most recent 10 out of 78 publications