The Retrovirus Research Center (RRC) is a facility that promote and stimulates research addressing the HIV and AIDS epidemic in Puerto Rico. The RRC is composed of a Leadership Core and a Laboratory Core. In addition it works intimately with the Data Management and Statistical Research Support Unit (DMSRSU), which manages a longitudinal database of over 4,000 patients with HIV infection. It's considered unique in Puerto Rico since it is the only one in which full Integration of the research effort with the health care delivery facility is In place.
The aim of the RRC Is to promote the study of HIV- Infection as a multidisciplinary research arena In which the clinical, immunological, virological, psychosocial and behavioral parameters need to be integrated Into a coherent research strategy. The center agglutinates multidisciplinary researchers Interesting In describing and understanding key elements of HIV infection according to an ecological view. The RRC has an important role In continuing the research agenda with this patient population with the goal of diminishing the spreading nature of the HIV epidemic In the Island. The Leadership Core coordinates and facilitates an Intellectually stimulating environment for HIV/AIDS research by playing a proactive role In generating hypothesis-driven studies. This multidisciplinary vision of the RRC is responsive to the vision of the National Institutes of Health their role of studying the complexity of diseases. Our objectives for the next five years will Include 1. Provide the support for the study of the multidimensional aspects of HIV Infection, by planning and stimulating HIV/AIDS research, scientific productivity and hypothesis driven studies. 2. Provide support for HIV research activities. The resources Include the HIV Data Registry, the specialized laboratory and the plasma and lymphocyte repository. 3. Contribute to the research development career of the RRC faculty members and research staff in coordination with the DMSRSU and the SRDU. 4. Continue to provide support for community Involvement In research activities. 5. Develop strategies to become a RCMI Independent HIV Research Center.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Research Centers in Minority Institutions Award (G12)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Universidad Central Del Caribe
United States
Zip Code
Huertas, Adriana; Wessinger, William D; Kucheryavykh, Yuri V et al. (2015) Quinine enhances the behavioral stimulant effect of cocaine in mice. Pharmacol Biochem Behav 129:26-33
Ferchmin, P A; Andino, Myrna; Reyes Salaman, Rebeca et al. (2014) 4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration. Neurotoxicology 44:80-90
Althoff, Keri N; Rebeiro, Peter; Brooks, John T et al. (2014) Disparities in the quality of HIV care when using US Department of Health and Human Services indicators. Clin Infect Dis 58:1185-9
Zayas-Santiago, Astrid; Agte, Silke; Rivera, Yomarie et al. (2014) Unidirectional photoreceptor-to-Müller glia coupling and unique K+ channel expression in Caiman retina. PLoS One 9:e97155
Ríos, Grissel; Estrada, Marcos; Mayor, Angel M et al. (2014) Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J 33:112-6
Rebeiro, Peter F; Horberg, Michael A; Gange, Stephen J et al. (2014) Strong agreement of nationally recommended retention measures from the Institute of Medicine and Department of Health and Human Services. PLoS One 9:e111772
Schikorski, Thomas (2014) Readily releasable vesicles recycle at the active zone of hippocampal synapses. Proc Natl Acad Sci U S A 111:5415-20
Skatchkov, Serguei N; Woodbury-Fariña, Michel A; Eaton, Misty (2014) The role of glia in stress: polyamines and brain disorders. Psychiatr Clin North Am 37:653-78
Santiago-Rodríguez, Eduardo J; Mayor, Angel M; Fernández-Santos, Diana M et al. (2014) Anemia in a cohort of HIV-infected Hispanics: prevalence, associated factors and impact on one-year mortality. BMC Res Notes 7:439
Sanabria-Rios, David J; Rivera-Torres, Yaritza; Maldonado-Dominguez, Gamalier et al. (2014) Antibacterial activity of 2-alkynoic fatty acids against multidrug-resistant bacteria. Chem Phys Lipids 178:84-91

Showing the most recent 10 out of 18 publications