Border Biomedical Research Center (BBRC). The University of Texas at El Paso (UTEP), in collaboration with regional academic, governmental and private groups, has as a goal, to sustain and grow extant BBRC infrastructure and programs to enable high quality research on health disparities prevalent on the U.S. Mexico border. This goal will be obtained through achievement of four specific objectives. These are to: (1) Focus on augmenting three research areas of strength to better understand causes and mechanisms. These "clusters" are (a) infectious diseases and immunity, (b) cancer and diseases caused by environmental toxicants, and (c) distinct neuro-modulation disorders. Pursuits will be with greater emphasis on epidemiology and collaborations with clinical and public health specialists. (2) Strengthen research infrastructure to enhance capabilities of growing numbers of investigators through (a) enhancement of multi-user core facilities for research in molecular and cell biology and consultation in biostatistics and bioinformatics, (b) creation of a new initiative, the Community Engagement Core, (c) recruitment of new faculty members to research border health issues, (d) development, professionally, of BBRC investigators, (e) implementation of a pilot grant program emphasizing inter-disciplinary research, and (f) establishment of an institution-wide seminar and a biennial international symposium that underscore through practice BBRC's heightened emphasis on community engagement, networking, collaboration and translational research. Included in infrastructure enhancement are physical plant components that support research, an administrative core to coordinate, manage and govern program components, and an evaluative component to assess progress in achieving program- and border health objectives. (3) Accentuate translation of BBRC research through greater emphasis in various BBRC activities, including teaching, of the interplay between basic and applied science and the importance of utility in laboratory discoveries. (4) Create, through collective BBRC activities, a nationally competitive research environment to support the doctoral program in Biological Sciences as a means to develop future researchers and amplify investigative manpower.

Public Health Relevance

Achieving the RCMI-BBRC goal and objectives will help create a healthier Paso de Norte border region by spearheading, sustaining and leveraging biomedical research and practice, and increasing the work force to develop countermeasures to health problems concentrated in the area but of national consequence, and provide a highly competitive faculty and training setting at UTEP to prepare minority students for entry into the biomedical research mainstream of the nation.

Agency
National Institute of Health (NIH)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12MD007592-21
Application #
8666298
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Rajapakse, Nishadi
Project Start
Project End
Budget Start
Budget End
Support Year
21
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Texas El Paso
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
El Paso
State
TX
Country
United States
Zip Code
79968
Liu, Xinxin; Chai, Yurong; Li, Jitian et al. (2014) Autoantibody response to a novel tumor-associated antigen p90/CIP2A in breast cancer immunodiagnosis. Tumour Biol 35:2661-7
Rico, Cyren M; Lee, Sang Chul; Rubenecia, Rosnah et al. (2014) Cerium oxide nanoparticles impact yield and modify nutritional parameters in wheat (Triticum aestivum L.). J Agric Food Chem 62:9669-75
Gant Jr, Vincent U; Moreno, Stephanie; Varela-Ramirez, Armando et al. (2014) Two membrane-associated regions within the Nodamura virus RNA-dependent RNA polymerase are critical for both mitochondrial localization and RNA replication. J Virol 88:5912-26
Liu, Mei; Zheng, Su-jun; Chen, Yu et al. (2014) Autoantibody response to murine double minute 2 protein in immunodiagnosis of hepatocellular carcinoma. J Immunol Res 2014:906532
Mariano, Vania Sammartino; Zorzetto-Fernandes, Andre Luiz; da Silva, Thiago Aparecido et al. (2014) Recognition of TLR2 N-glycans: critical role in ArtinM immunomodulatory activity. PLoS One 9:e98512
Roy, Debarshi; Kabiraj, Parijat; Pal, Rituraj (2014) EF24 prevents rotenone-induced estrogenic status alteration in breast cancer. Cell Biol Int 38:511-9
Liu, Mei; Liu, Xinxin; Ren, Pengfei et al. (2014) A cancer-related protein 14-3-3? is a potential tumor-associated antigen in immunodiagnosis of hepatocellular carcinoma. Tumour Biol 35:4247-56
Dai, Liping; Li, Jitian; Ortega, Rosalia et al. (2014) Preferential autoimmune response in prostate cancer to cyclin B1 in a panel of tumor-associated antigens. J Immunol Res 2014:827827
Liu, Xinxin; Ye, Hua; Li, Liuxia et al. (2014) Humoral autoimmune responses to insulin-like growth factor II mRNA-binding proteins IMP1 and p62/IMP2 in ovarian cancer. J Immunol Res 2014:326593
Chai, Yurong; Liu, Xinxin; Dai, Liping et al. (2014) Overexpression of HCC1/CAPER? may play a role in lung cancer carcinogenesis. Tumour Biol 35:6311-7

Showing the most recent 10 out of 52 publications