The Howard University (HU) biomedical research goals include the pursuit of the resolution of diseases that disproportionately affect African Americans and to encourage multidisciplinary approaches to research. While diseases which disproportionately impact African Americans are many and varied, the HU biomedical research effort is primarily, but not exclusively, focused on cancer, cardiovascular diseases, neurological disorders, and infectious diseases, including HIV/AIDS. Critical to HU achieving these goals is the availability of specialty core facilities, enhanced opportunities for collaborative research, ad enhanced professional development of its investigator community. The HU RCMI Program will contribute to meeting these critical needs by providing core facility resources for computational biology, bioinformatics, molecular, magnetic, and optical imaging, and proteomics. In support of the need to provide enhanced collaborative opportunities, the RCMI Program will provide a pilots project program for the support of collaborative studies and provide trainings to the HU community in the Science of Collaboration or Team Science. Additionally, concierge support will be provided to assist HU faculty access core facilities in the RCMI Translational Research Network (RTRN) and Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) communities. Roundtable discussions will be held to stimulate and encourage collaborative efforts among HU faculty. The HU RCMI Program will also provide enhanced bundled core services which require the collaborative efforts of multiple core facilities, which will both enhance research capacity and provide new pathways for collaboration among facility users. The RCMI Program will provide professional development training opportunities for faculty and Post-doctoral fellows. The faculty track will include a seminar/workshop series that will be centered around the granting process and proposal development. Additionally, the faculty track will include mentoring for junior faculty. The post-doctoral track will provide a seminar/workshop series that will cover proposal development, managing the publication process, time management, and career planning. The progress of each RCMI Program activity will be guided by a set of milestones and timelines which will be subject to annual evaluations by an external evaluator. Finally, all activities of the RCMI Program will be provided administrative, coordination and logistical support from an Administrative Core.

Public Health Relevance

The RCMI Program will increase Howard University's contribution to the resolution of those diseases that disproportionately affect minority populations such as cancer, cardiovascular diseases, neurological disorders, and infectious diseases, including HIV/AIDS, by providing core facilities, collaboration enhancement and professional development opportunities for Howard faculty.

Agency
National Institute of Health (NIH)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12MD007597-26
Application #
8666905
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Mcclure, Shelia A
Project Start
Project End
Budget Start
Budget End
Support Year
26
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Howard University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Washington
State
DC
Country
United States
Zip Code
20059
Barfield, Whitney L; Uaesoontrachoon, Kitipong; Wu, Chung-Sheih et al. (2014) Eccentric muscle challenge shows osteopontin polymorphism modulation of muscle damage. Hum Mol Genet 23:4043-50
Ilinykh, Philipp A; Tigabu, Bersabeh; Ivanov, Andrey et al. (2014) Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription. J Biol Chem 289:22723-38
Lee, Kwang-Soo; Park, Jong-Lyul; Lee, Kwanbok et al. (2014) nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer. Oncotarget 5:3944-55
Huo, Shuaidong; Jin, Shubin; Ma, Xiaowei et al. (2014) Ultrasmall gold nanoparticles as carriers for nucleus-based gene therapy due to size-dependent nuclear entry. ACS Nano 8:5852-62
Bond Jr, Vernon; Curry, Bryan H; Adams, Richard G et al. (2014) Cardiorespiratory function associated with dietary nitrate supplementation. Appl Physiol Nutr Metab 39:168-72
Ashktorab, Hassan; Paydar, Mansour; Yazdi, Shahla et al. (2014) BMI and the risk of colorectal adenoma in African-Americans. Obesity (Silver Spring) 22:1387-91
Nekhai, Sergei; Hynes, Alla; Ammosova, Tatiana et al. (2014) A128: hierarchical clustering methodology for exploration of proteomic profile in tears: seeking for markers of uveitis associated with juvenile idiopathic arthritis. Arthritis Rheumatol 66 Suppl 11:S168
Ashenafi, Meseret; Ammosova, Tatiana; Nekhai, Sergei et al. (2014) Purification and characterization of aminoglycoside phosphotransferase APH(6)-Id, a streptomycin-inactivating enzyme. Mol Cell Biochem 387:207-16
Shim, Jung Ho; Yoon, Jung Hwan; Choi, Sung Sook et al. (2014) The effect of Helicobacter pylori CagA on the HER-2 copy number and expression in gastric cancer. Gene 546:288-96
Zhang, Xu; Zhang, Wei; Ma, Shwu-Fan et al. (2014) Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing. Blood Cells Mol Dis 52:35-45

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