As the principal U.S. institution of higher education engaged in biomedical and bio-behavioral research within the Pacific basin, the University of Hawaii at Manoa (UHM) seeks continued support from the Research Centers in Minority Institutions (RCMI) Program of the National Institutes of Health, to further develop research excellence in biomedicine by establishing an interdisciplinary network aimed at linking basic sciences, clinical medicine and translational research discoveries, with the goal of Attain Lasting Optimal Health for All (ALOHA), and with specific emphasis on addressing health disparities in underserved minority populations. Designated the Bioscience Research Infrastructure Development for Grant Enhancement and Success (BRIDGES), the UHM RCMI Program for the 2012-2017 cycle will embrace the spirit and tenets of the NIH Roadmap by creating interdisciplinary collaborative research networks employing emerging technologies for basic, clinical and translational sciences. Specifically, the research activities focusing on Collaborations and Partnerships and Professional Development, and the infrastructure cores in proteomics, magnetic resonance imaging, electrophysiology and behavior, microscopy, histopathology, human tissue biorepositories, bioinformatics, biostatistics and research ethics will rely heavily on interdisciplinary collaborations and intellectual exchange between basic scientists and clinicians, applying knowledge of human biology, physiology, biochemistry, molecular biology and fundamental principles of physics and chemistry, to develop novel and improved disease-specific diagnostic tests, therapeutic interventions and preventive strategies for health disparities of regional and national importance. These activities are designed to closely complement the basic science, clinical and patient-oriented activities of the RCMI Clinical Translational Research Center, (RCTR RMATRIX), the Center for Native and Pacific Health Disparities Research (CNPHDR), the Hawaii Statewide Research and Education Partnership (INBRE HSREP), and the Centers of Biomedical Research Excellence (COBRE). The RCMI BRIDGES Program will better position UHM to participate fully in the RCMI Translational Research Network and to ultimately secure a Clinical and Translational Sciences Award. Strong leadership has been identified for each of the Activities and Cores. Finally, complementary technical cores are being developed and expanded to achieve greater success in competing for mainstream extramural NIH funding for research and training.
The overall objectives of the RCMI Program at UHM are to create and strengthen expertise, education, training and infrastructure for biomedical and behavioral research that promises to improve the diagnosis, prevention, and treatment of diseases, especially those associated with health disparities in minority populations in Hawaii.
|Sentell, Tetine; Miyamura, Jill; Ahn, Hyeong Jun et al. (2015) Potentially Preventable Hospitalizations for Congestive Heart Failure Among Asian Americans and Pacific Islanders in Hawai'i. J Immigr Minor Health 17:1289-97|
|Meiler, Svenja; Baumer, Yvonne; Toulmin, Emma et al. (2015) MicroRNA 302a is a novel modulator of cholesterol homeostasis and atherosclerosis. Arterioscler Thromb Vasc Biol 35:323-31|
|Gumus, Kazim; Keating, Brian; White, Nathan et al. (2015) Comparison of optical and MR-based tracking. Magn Reson Med 74:894-902|
|Shikuma, Cecilia M; Gangcuangco, Louie Mar A; Killebrew, Deirdre A et al. (2014) The role of HIV and monocytes/macrophages in adipose tissue biology. J Acquir Immune Defic Syndr 65:151-9|
|Seale, Lucia A; Gilman, Christy L; Moorman, Benjamin P et al. (2014) Effects of acclimation salinity on the expression of selenoproteins in the tilapia, Oreochromis mossambicus. J Trace Elem Med Biol 28:284-92|
|Sentell, Tetine; Zhang, Wei; Davis, James et al. (2014) The influence of community and individual health literacy on self-reported health status. J Gen Intern Med 29:298-304|
|Pitts, Matthew W; Byrns, China N; Ogawa-Wong, Ashley N et al. (2014) Selenoproteins in nervous system development and function. Biol Trace Elem Res 161:231-45|
|Yang, Yuyi; Woodward, Lee Ann; Li, Qing X et al. (2014) Concentrations, source and risk assessment of polycyclic aromatic hydrocarbons in soils from midway atoll, north pacific ocean. PLoS One 9:e86441|
|Terada, Keith Y; Elia, Jennifer; Kim, Robert et al. (2014) Abnormal CA-125 levels in menopausal women without ovarian cancer. Gynecol Oncol 135:34-7|
|Tandon, Ravi; Chew, Glen M; Byron, Mary M et al. (2014) Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers. AIDS Res Hum Retroviruses 30:654-64|
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