The Morehouse School of Medicine G12 Multidisciplinary Biomedical Research Center (G12/MBRC) research goal is to build a critical level of biomedical research capability, productivity, and training that will allow MSM to pursue multidisciplinary approaches to discovery science that translate into the amelioration of health disparities. MSM has experienced growth and success of its research enterprise over the past decade based on a strategic plan that focuses our talent and resources in discrete areas. The G12/MBRC proposal builds on this foundation developed with careful stewardship and investments of RCMI resources. Our approach is to enhance the research capacity in biomedical science by building effective inter- and intra-institutional partnerships synergizing/leveraging the collective strengths of our faculty, trainees, students and collaborators. The G12/MBRC institution-wide framework and key activities are designed to promote transformative changes in our research environment enhancing our research capacity in biomedical research, ultimatelly enhancing our clinical/translational science through the following specific aims:
Aim I : Transform Our Institution: Provide an organizational framework; Support a culture of collaboration between institutional units and between institutions; rework the TTP financial framework to enhance research development in multidisciplinary biomedical and translational science.
Aim II : Transform Our Research Environment: Provide a robust research infrastructure/training environment fostering innovative, multidisciplinary biomedical/translational research.
Aim III : Transform the Community of Biomedical Scientists: Provide an institution-wide resource that: (i) leverages existing training programs and integrates research project support and mentorship enhancinig research training/career development; (ii) incentivizes collaborative, multidisciplinary research; (iii) synergizes research support and core technology mentorship to enhance research training/career development and expand the intellectual property portfolio at MSM. Overall, the implementation of these specific aims will enable MSM to fulfill its long term goal of translating discovery science into community-based solutions that ameliorate health disparities.

Public Health Relevance

Minority-serving academic health centers, such as MSM, are strategically poised to make important scientific contributions addressing the devastating problem of racial/ethnic health disparities. The G12/MBRC program will enable MSM investigators to reach that critical level of research capability/capacity necessary to pursue discovery science translating to improvements in the health status of minority communities we serve.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Centers in Minority Institutions Award (G12)
Project #
3G12MD007602-30S2
Application #
9282877
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Sayre, Michael
Project Start
1997-07-07
Project End
2017-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
30
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Morehouse School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Wallace, LaShanale; Cherian, Anju M; Adamson, Paula et al. (2018) Comparison of Pre- and Post-translational Expressions of COXIV-1 and MT-ATPase 6 Genes in Colorectal Adenoma-Carcinoma Tissues. J Carcinog Mutagen 9:
Singh, Santosh Kumar; Mishra, Manoj K; Eltoum, Isam-Eldin A et al. (2018) CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells. Sci Rep 8:1323
Greene, Sarah J (2018) The use and effectiveness of interactive progressive drawing in anatomy education. Anat Sci Educ 11:445-460
Liu, Mingli; Inoue, Koichi; Leng, Tiandong et al. (2017) ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway. Oncotarget 8:8283-8293
Huang, Ming-Bo; Gonzalez, Ruben R; Lillard, James et al. (2017) Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells. Oncotarget 8:11302-11315
Singh, Santosh Kumar; Banerjee, Saswati; Acosta, Edward P et al. (2017) Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway. Oncotarget 8:17216-17228
Banerjee, Saswati; Singh, Santosh K; Chowdhury, Indrajit et al. (2017) Combinatorial effect of curcumin with docetaxel modulates apoptotic and cell survival molecules in prostate cancer. Front Biosci (Elite Ed) 9:235-245
Eckard, Allison Ross; Thierry-Palmer, Myrtle; Silvestrov, Natalia et al. (2017) Effects of cholecalciferol supplementation on serum and urinary vitamin D metabolites and binding protein in HIV-infected youth. J Steroid Biochem Mol Biol 168:38-48
Hu, Guoku; Yelamanchili, Sowmya; Kashanchi, Fatah et al. (2017) Proceedings of the 2017 ISEV symposium on ""HIV, NeuroHIV, drug abuse, & EVs"". J Neurovirol 23:935-940
Laurent, Virgine; Sengupta, Anamika; Sánchez-Bretaño, Aída et al. (2017) Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium. Exp Eye Res 165:90-95

Showing the most recent 10 out of 82 publications