This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The RCMI-supported core shared research facilities at the Center for Study of Gene Structure and Function at Hunter College provide essential services to support the first-class research of our scientists. It is imperative that we improve the strengths of the facilities by constantly updating the equipment and expertise of the managers and users. The facilities also allow us to compete for topnotch scientists, highly qualified graduate students and post-doctoral researchers who contribute to our research output. An environment where researchers compete successfully for outside funding is critical to our overall aims, and with the addition of new and planned facilities we will be able to better address the problem of health disparities in the United States. In the next grant period, we plan to hire essential personnel and to upgrade the equipment in the following facilities: Bioimaging, Animal Care, Genomics, Internet2 and the Gene Center Local Area Network (LAN). Our plans include improving these core shared research facilities as well as the Fluorescence Activated Cell Sorting (FACS), the Nuclear Magnetic Resonance (NMR) and the X-Ray Diffraction Facilities. These improvements require the following: (a) supporting service contracts with grant funds and users'fees;(b) upgrading the skills of facilities'managers through advanced training, continuing education, external collaborations and professional certifications;and (c) upgrading standard operating procedures, record-keeping, manuals, and websites. Improving our core facilities will help us to maximize our scientific output and attain the goals of the RCMI Program.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12RR003037-26A1
Application #
8357180
Study Section
Special Emphasis Panel (ZRR1-RI-B (02))
Project Start
2011-09-15
Project End
2012-06-30
Budget Start
2011-09-15
Budget End
2012-06-30
Support Year
26
Fiscal Year
2011
Total Cost
$432,606
Indirect Cost
Name
Hunter College
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
620127915
City
New York
State
NY
Country
United States
Zip Code
10065
Avila, Jorge A; Alliger, Amber A; Carvajal, Brigett et al. (2017) Estradiol rapidly increases GluA2-mushroom spines and decreases GluA2-filopodia spines in hippocampus CA1. Hippocampus 27:1224-1229
Kiprowska, Magdalena J; Stepanova, Anna; Todaro, Dustin R et al. (2017) Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta 1863:1157-1170
Babkirk, Sarah; Luehring-Jones, Peter; Dennis-Tiwary, Tracy A (2016) Computer-mediated communication preferences predict biobehavioral measures of social-emotional functioning. Soc Neurosci 11:637-51
Urbanski, Mateusz M; Kingsbury, Lyle; Moussouros, Daniel et al. (2016) Myelinating glia differentiation is regulated by extracellular matrix elasticity. Sci Rep 6:33751
He, Huifang; Deng, Kangwen; Siddiq, Mustafa M et al. (2016) Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5. J Neurosci 36:3079-91
Carbone, Lorenzo; Verrelli, Roberta; Gobet, Mallory et al. (2016) Insight on the Li2S electrochemical process in a composite configuration electrode. New J Chem 40:2935-2943
IƱiguez, Sergio D; Aubry, Antonio; Riggs, Lace M et al. (2016) Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice. Neurobiol Stress 5:54-64
Yoon, Seungyeon A; Weierich, Mariann R (2016) Salivary biomarkers of neural hypervigilance in trauma-exposed women. Psychoneuroendocrinology 63:17-25
Oliver, Chicora F; Kabitzke, Patricia; Serrano, Peter et al. (2016) Repeated recall and PKM? maintain fear memories in juvenile rats. Learn Mem 23:710-713
Jacome, Luis F; Barateli, Ketti; Buitrago, Dina et al. (2016) Gonadal Hormones Rapidly Enhance Spatial Memory and Increase Hippocampal Spine Density in Male Rats. Endocrinology 157:1357-62

Showing the most recent 10 out of 216 publications