This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The proposed goal of the Program for the next five years is to continue the development of competitive research on the Medical Sciences Campus, by focusing on the development of a strong infrastructure for conducting multidisciplinary collaborative research studies through the establishment of clusters of excellence in health disparities affecting the Puerto Rican population. Addressing and understanding these differences is critical for evaluating the factors involved and for improving health status and quality of life. Research approaches to address this goal will range from the molecular to the clinical level. Toward this end, the RCMI Program proposes to: (1) develop infrastructure and provide support services to facilitate the conduct of multidisciplinary collaborative research in health disparities;(2) target specific areas of research and provide initial funding for developing these research activities;(3) promote the professional development of junior research faculty working on this area. The Program will have three components: a Division of Research Resources, which will include infrastructure activities that provide research support services. These service activities will include, among others: the RCMI Proteomics Discovery Core Facility;the Center for Molecular Genetics and Infectious Diseases Research, the Enhancement of Neurogenetics Research at the Institute of Neurobiology, and the Collaborative Technologies Initiative for which funding is requested. The Division of Research Development will help achieve the second objective, by providing a focal point for research activities conducted by junior investigators. Two pilot projects in the area of infectious diseases were identified for development. The third objective, professional development of promising research faculty, will be approached through a series of activities including a mentoring program designed to foster the research career development. The Division of Advancement in Research will oversee the mentoring program and will offer a course for strengthening research skills, will provide scientific editing services, will train on how to protect and commercializing ideas, and will develop a comprehensive multidisciplinary collaborative research seminar series. Many of these activities will be offered utilizing the information technology infrastructure developed by the Center for Information Architecture in Research during the current cycle.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
2G12RR003051-26
Application #
8357159
Study Section
Special Emphasis Panel (ZRR1-RI-B (02))
Project Start
2011-09-15
Project End
2012-07-31
Budget Start
2011-09-15
Budget End
2012-07-31
Support Year
26
Fiscal Year
2011
Total Cost
$163,897
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Pharmacology
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
00936
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Palacios, Cristina; Daniel, Carrie R; Tirado-Gómez, Maribel et al. (2017) Dietary Patterns in Puerto Rican and Mexican-American Breast Cancer Survivors: A Pilot Study. J Immigr Minor Health 19:341-348
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Díaz-Ayala, Ramonita; Torres-González, Lisa; Pietri, Ruth et al. (2017) Engineered (Lys)6-Tagged Recombinant Sulfide-Reactive Hemoglobin I for Covalent Immobilization at Multiwalled Carbon Nanotubes. ACS Omega 2:9021-9032
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Ballista-Hernández, Joan; Martínez-Ferrer, Margaly; Vélez, Roman et al. (2017) Mitochondrial DNA Integrity Is Maintained by APE1 in Carcinogen-Induced Colorectal Cancer. Mol Cancer Res 15:831-841
Lozada-Delgado, Eunice L; Grafals-Ruiz, Nilmary; Vivas-Mejía, Pablo E (2017) RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials. Life Sci 188:26-36
Martínez, Osmarie; Bravo Cruz, Ariana; Santos, Saritza et al. (2017) Vaccination with a codon-optimized A27L-containing plasmid decreases virus replication and dissemination after vaccinia virus challenge. Vaccine 35:6007-6014
Nogueras-Ortiz, Carlos; Roman-Vendrell, Cristina; Mateo-Semidey, Gabriel E et al. (2017) Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell 28:3554-3561

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