This revised Mentored Research Scientist Development Award (KOI) application (#1 KOI AA015137-01) will launch Dr. Pagano's career into alcohol treatment research, with a focus on AA-related behaviors and social dynamics that facilitate long-term recovery from alcoholism. Of particular interest is the role of prosocial behaviors among AA members that mobilize drinking reduction and sustain abstinence. This application describes a tightly integrated career development plan that includes a specific plan for publications, and a research project, with mentors of international reputation who are committed to the success of the candidate: Drs. Robert Stout, Robert Swift, J. Scott Tonigan, and Jane Piliavin. The career plan consists of 4 elements, sequenced to enhance the success of the research plan: (1) didactic academic training in the epidemiology and neuropsychology of alcoholism, alcoholism and its comorbidities, alcoholism treatment and intervention strategies, and ethical issues in conducting alcoholism research, (2) in-depth study of alternative methodological approaches used in alcohol research, (3) direct research experiences, and (4) statistical training. Combined, these activities will increase Dr. Pagano's understanding of the biological, psychological, and social factors associated with the etiology and recovery from alcoholism;develop clinical skills;increase understanding of the nature and theory of clinical interventions;and advance the candidate's statistical skills for analyses of longitudinal data. The proposed research plan has three phases, with the final goal of developing a psychometrically validated self-report measure of prosocial behaviors, the Prosocial Behavior Questionnaire (PBQ). Phase I and II involve instrument development, refinement, and data collection within the context of an ongoing NIAAA funded study (CME: #AA09907-09) and a non-treatment seeking community sample. Phase in involves psychometric examination of the PBQ, the relationship between changes in PBQ scores and drinking outcomes, and comparison of PBQ scores among CME1 participants to participants from a community sample. Accomplishment of these aims will provide the necessary foundation for a prospective study of the longitudinal relationship between prosocial behavior and later drinking reduction and improved recidivism, an objective Dr. Pagano will address in an R01 application in year 4.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Research Scientist Development Award - Research & Training (K01)
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Study Section
Health Services Research Review Subcommittee (AA)
Program Officer
Martinelli, Angela
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Case Western Reserve University
Schools of Medicine
United States
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Johnson, Byron R; Pagano, Maria E; Lee, Matthew T et al. (2018) Alone on the Inside: The Impact of Social Isolation and Helping Others on AOD Use and Criminal Activity. Youth Soc 50:529-550
Post, Stephen G; Pagano, Maria E; Lee, Matthew T et al. (2016) Humility and 12-Step Recovery: A Prolegomenon for the Empirical Investigation of a Cardinal Virtue in Alcoholics Anonymous. Alcohol Treat Q 34:262-273
Lee, Matthew T; Pagano, Maria E; Johnson, Byron R et al. (2016) Love and Service in Adolescent Addiction Recovery. Alcohol Treat Q 34:197-222
Johnson, Byron R; Lee, Matthew T; Pagano, Maria E et al. (2016) Positive Criminology and Rethinking the Response to Adolescent Addiction: Evidence on the Role of Social Support, Religiosity, and Service to Others. Int J Criminol Sociol 5:172-181
Pagano, Maria E; Swaringen, Shanna E; Frank, Scott H (2016) Low Other-Regard and Adolescent Addiction. J Child Adolesc Subst Abuse 25:268-276
Chasser, Yvonne M (2016) Profiles of Youth with PTSD and Addiction. J Child Adolesc Subst Abuse 25:448-454
Pagano, Maria E; Delos-Reyes, Christina M; Wasilow, Sherry et al. (2016) Smoking Cessation and Adolescent Treatment Response With Comorbid ADHD. J Subst Abuse Treat 70:21-27
Pagano, Maria E; Maietti, Candice M; Levine, Alan D (2015) Risk factors of repeated infectious disease incidence among substance-dependent girls and boys court-referred to treatment. Am J Drug Alcohol Abuse 41:230-6
Pagano, Maria E; Wang, Alexandra R; Rowles, Brieana M et al. (2015) Social anxiety and peer helping in adolescent addiction treatment. Alcohol Clin Exp Res 39:887-95
Lee, Matthew T; Veta, Paige S; Johnson, Byron R et al. (2014) Daily Spiritual Experiences and Adolescent Treatment Response. Alcohol Treat Q 32:271-298

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