This four-year FIC Development Award will foster the candidate's ability to achieve her long-term goal of becoming an independent interdisciplinary researcher. Ultimately she will develop the skills, knowledge and experience to pursue an international collaborative research career focused on global health challenges, particularly environmental and nutritional risk factors for child behavior problems. This goal will be achieved through involvment in a mentor-oriented international collaborative research study, through pursuing research activities, course work, laboratory training, and conferences/workshops. The proposed training plan aims to build on the candidate's prior research experience with new training in understanding the impact of environmental toxicity and / or micromalnutrition on children's behavior problems. The five specific training goals are to (1) expand new knowledge on environment toxicity, (2) receive further training in nutrition assessment and its implication in child behavior problems, (3) obtain further training in psychopathology, (4) enhance skills in research methodology and advanced statistics, and (5) develop new knowledge and skills in international collaborative research and cross-cultural research. The proposed research plan aims to examine the link between both environmental toxicity and micronutrition deficiency and childhood externalizing behavior. The four specific aims are to: (1) assess the direct effect of lead exposure and micronutrient deficiency on children's externalizing behavior;(2) examine the interactive effect of biological and psychosocial risk factors on childhood externalizing behavior;(3) test which factors mediate the above direct and interactive effects;and (4) identify the specific components of environmental toxicity/micronutrient deficiency and psychosocial risk factors which give rise to childhood externalizing behavior. Hypotheses will be tested in the context of an ongoing international collaborative prospective study of 780 five to six-year-old male and female Chinese kindergarten children. Measures include blood levels of lead and micronutrients, IQ, psychosocial confounds, and behavior problem checklists. Structural Equation Modeling will be used for data analysis. / In summary, this proposed mentored international collaborative research/ training will target three global public health problems: environmental toxicity, micromalnutrition, and childhood behavior disorder, a focus consistent with mission of FIC of addressing global health research priorities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
3K01ES015877-04S1
Application #
7883811
Study Section
Special Emphasis Panel (ZRG1-ICP-3 (51))
Program Officer
Shreffler, Carol K
Project Start
2009-09-01
Project End
2011-08-31
Budget Start
2009-09-01
Budget End
2011-08-31
Support Year
4
Fiscal Year
2009
Total Cost
$99,140
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Nursing
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Ye, Tianpeng; Cui, Naixue; Yang, Wen et al. (2018) Evaluation of the Factor Structure of the Adolescent Stress Questionnaire in Chinese Adolescents. Psychol Rep :33294118792686
Cui, Naixue; Deatrick, Janet A; Liu, Jianghong (2018) Maternal and paternal physical abuse: Unique and joint associations with child behavioral problems. Child Abuse Negl 76:524-532
Ji, Xiaopeng; Li, Junxin; Liu, Jianghong (2018) The Relationship Between Midday Napping And Neurocognitive Function in Early Adolescents. Behav Sleep Med :1-15
Liu, Jianghong; Cui, Ying; Li, Linda et al. (2017) The mediating role of sleep in the fish consumption - cognitive functioning relationship: a cohort study. Sci Rep 7:17961
Ji, Xiaopeng; Cui, Naixue; Liu, Jianghong (2017) Neurocognitive Function Is Associated With Serum Iron Status in Early Adolescents. Biol Res Nurs 19:269-277
Cui, Naixue; Liu, Jianghong (2016) Cognitive and behavioral risk factors for child physical abuse among Chinese children: a multiple-informant study. Child Adolesc Psychiatry Ment Health 10:36
Tuvblad, Catherine; Dhamija, Devika; Berntsen, Leslie et al. (2016) Cross-Cultural Validation of the Reactive-Proactive Aggression Questionnaire (RPQ) Using Four Large Samples from the US, Hong Kong, and China. J Psychopathol Behav Assess 38:48-55
Liu, Jianghong; Liu, Xianchen; Ji, Xiaopeng et al. (2016) Sleep disordered breathing symptoms and daytime sleepiness are associated with emotional problems and poor school performance in children. Psychiatry Res 242:218-225
Cui, Naixue; Xue, Jia; Connolly, Cynthia A et al. (2016) Does the gender of parent or child matter in child maltreatment in China? Child Abuse Negl 54:1-9
Liu, Jianghong; Lynn, Richard (2015) Chinese sex differences in intelligence: Some new evidence. Pers Individ Dif 75:90-93

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