The candidate's long-term career objective is to investigate biomechanical factors contributing to musculoskeletal dysfunction, in order to refine current clinical treatment approaches and develop novel scientifically founded rehabilitation interventions. A five-year research and training plan developed with the primary mentor and a team of experienced scientists will expand the candidate's scientific background in biomechanics and musculoskeletal modeling, enrich her direct research skills and experience in the scientific process, promote integration of research findings to clinical practice, and advance skills necessary for becoming an independent investigator. The long-term objective of the research plan is to develop and test the effectiveness of biomechanically based rehabilitation strategies for improving upper extremity function and reducing pain and disability in persons with shoulder pathologies related to abnormal shoulder movement patterns. In-vivo 3-D full shoulder complex kinematics (thorax, clavicle, scapula, and humerus) during arm elevation will be collected from healthy and symptomatic subjects and integrated with a state of the art shoulder model to describe the 3-D muscle function of selected shoulder muscles, allowing comparisons among muscles for their relative biomechanical ability to reduce shoulder kinematic deviations, or contribute to deviations if producing excess or inadequate force (Aim 1). Computerized Tomography scans of the shoulder complex structures will be taken and imaging data combined with the kinematic data, allowing determination of the effects of abnormal kinematics on the available volume of the subacromial space, providing insight into how specific kinematic deviations create impingement of soft tissue structures (Aim 2). Determining and demonstrating muscle activations that can improve scapular kinematics and reduce subacromial impingement can provide a template for scientifically based intervention approaches that can be further tested through clinical trials.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01HD042491-05
Application #
7226766
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Nitkin, Ralph M
Project Start
2003-06-01
Project End
2009-02-28
Budget Start
2007-06-01
Budget End
2009-02-28
Support Year
5
Fiscal Year
2007
Total Cost
$115,053
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Physical Medicine & Rehab
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Seth, Ajay; Matias, Ricardo; Veloso, António P et al. (2016) A Biomechanical Model of the Scapulothoracic Joint to Accurately Capture Scapular Kinematics during Shoulder Movements. PLoS One 11:e0141028
Lawrence, Rebekah L; Braman, Jonathan P; Staker, Justin L et al. (2014) Comparison of 3-dimensional shoulder complex kinematics in individuals with and without shoulder pain, part 2: glenohumeral joint. J Orthop Sports Phys Ther 44:646-55, B1-3
Lawrence, Rebekah L; Braman, Jonathan P; Laprade, Robert F et al. (2014) Comparison of 3-dimensional shoulder complex kinematics in individuals with and without shoulder pain, part 1: sternoclavicular, acromioclavicular, and scapulothoracic joints. J Orthop Sports Phys Ther 44:636-45, A1-8
Hamming, David; Braman, Jonathan P; Phadke, Vandana et al. (2012) The accuracy of measuring glenohumeral motion with a surface humeral cuff. J Biomech 45:1161-8
Ludewig, Paula M; Braman, Jonathan P (2011) Shoulder impingement: biomechanical considerations in rehabilitation. Man Ther 16:33-9
Phadke, Vandana; Braman, Jonathan P; LaPrade, Robert F et al. (2011) Comparison of glenohumeral motion using different rotation sequences. J Biomech 44:700-5
Ludewig, Paula M; Hassett, Daniel R; Laprade, Robert F et al. (2010) Comparison of scapular local coordinate systems. Clin Biomech (Bristol, Avon) 25:415-21
Braman, Jonathan P; Thomas, Brian M; Laprade, Robert F et al. (2010) Three-dimensional in vivo kinematics of an osteoarthritic shoulder before and after total shoulder arthroplasty. Knee Surg Sports Traumatol Arthrosc 18:1774-8
Lunden, Jason B; Braman, Jonathan P; Laprade, Robert F et al. (2010) Shoulder kinematics during the wall push-up plus exercise. J Shoulder Elbow Surg 19:216-23
Braman, Jonathan P; Engel, Sean C; Laprade, Robert F et al. (2009) In vivo assessment of scapulohumeral rhythm during unconstrained overhead reaching in asymptomatic subjects. J Shoulder Elbow Surg 18:960-7

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