This Mentored Research Scientist Development Award (K01) will enable the candidate to independently conduct longitudinal high-risk research on emotion regulatory risk factors for child and adolescent depression. Early-onset depression is a disabling condition that is disturbingly common among adolescents of depressed parents. Research suggests that both neurobehavioral systems and social-interactional processes involved in emotional reactivity and regulation play a role in the transmission of risk for depression from parents to adolescents. Understanding the pathways by which these factors interact to contribute to depression onset is crucial for developing prevention and intervention approaches for this population. To address this need, the candidate will pursue training in developmental affective neuroscience, the assessment of dyadic affective behavior, and longitudinal statistical modeling. Training will be accomplished via (a) meetings and guided readings with mentor Ronald Dahl, M.D., co-mentor Daniel Shaw, Ph.D., and an expert team of internal and external consultants; (b) formal coursework; (c) supervised hands-on experience in the collection and analysis of data using behavioral observation and psychophysiological methodologies; and (d) attendance at local and national conferences, journal clubs, and research network meetings. The proposed research will utilize observational, psychophysiological (task-evoked pupillary responses, event- """"""""elated potentials), and questionnaire measures to examine maternal socialization of emotion regulation and adolescent emotional reactivity among depressed and nondepressed mothers and their early adolescent offspring. The research will also examine the interplay of these factors in contributing to adolescents' depressive symptomatology over time. These training activities will complement the candidate's background in clinical/developmental psychology and place the candidate in a position to conduct integrative research on social and neurobehavioral factors in the etiology of child and adolescent depression.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01MH073077-03
Application #
7169632
Study Section
Psychosocial Development, Risk and Prevention Study Section (PDRP)
Program Officer
Delcarmen-Wiggins, Rebecca
Project Start
2005-02-01
Project End
2010-01-31
Budget Start
2007-02-01
Budget End
2008-01-31
Support Year
3
Fiscal Year
2007
Total Cost
$138,558
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Olino, Thomas M; McMakin, Dana L; Nicely, Terri A et al. (2016) Maternal Depression, Parenting, and Youth Depressive Symptoms: Mediation and Moderation in a Short-Term Longitudinal Study. J Clin Child Adolesc Psychol 45:279-90
Belleau, Emily L; Phillips, Mary L; Birmaher, Boris et al. (2013) Aberrant executive attention in unaffected youth at familial risk for mood disorders. J Affect Disord 147:397-400
Silk, Jennifer S; Ziegler, Melissa L; Whalen, Diana J et al. (2009) Expressed emotion in mothers of currently depressed, remitted, high-risk, and low-risk youth: links to child depression status and longitudinal course. J Clin Child Adolesc Psychol 38:36-47
Silk, Jennifer S; Siegle, Greg J; Whalen, Diana J et al. (2009) Pubertal changes in emotional information processing: pupillary, behavioral, and subjective evidence during emotional word identification. Dev Psychopathol 21:7-26
Whalen, Diana J; Silk, Jennifer S; Semel, Mara et al. (2008) Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls. J Pediatr Psychol 33:358-67
Morris, Amanda Sheffield; Silk, Jennifer S; Steinberg, Laurence et al. (2007) The Role of the Family Context in the Development of Emotion Regulation. Soc Dev 16:361-388
Silk, Jennifer S; Dahl, Ronald E; Ryan, Neal D et al. (2007) Pupillary reactivity to emotional information in child and adolescent depression: links to clinical and ecological measures. Am J Psychiatry 164:1873-80