I am committed to a career in HIV/STD prevention research. To become a fully independent investigator, I am applying for the NIMH Mentored Research Scientist Development Award (K01) to augment my training and research in HIV/STD prevention research for vulnerable adolescents. Towards this goal, I will participate in courses, workshops, seminars, and mentoring meetings to enhance my existing knowledge and research skills, and acquire new knowledge and research skills specific to the design, implementation, adaptation and evaluation of HIV/STD prevention programs for adolescents. My proposed research plan, to be conducted at Emory University and the Fulton County Department of Health and Wellness, in Atlanta, Georgia, with the guidance of my Mentors (Primary Mentor: R. DiClemente, Co-Mentors: G. Wingood and S. Kalichman), can contribute significantly to the field of adolescent HIV prevention science in substantive and practical ways. Study 1 is a mixed-method study patterned after research conducted by my Co-Mentor (Dr. Kalichman), designed to: 1) identify the proportion of African-American female adolescents exposed to an HIV intervention that do not change their condom use, and 2) describe the personal, behavioral and psychosocial factors associated with "failure to change" condom use following an HIV intervention. Data from Study 1 directly informs Study 2. In Study 2, I will adapt an existing effective gender and culturally tailored adolescent HIV intervention developed by my Mentors (Dr. DiClemente, &Dr. Wingood), to enhance its efficacy for promoting condom use among African-American female adolescents who did not change their condom use after participating in an HIV intervention. The adaptation process will be guided by a sequential and systematic adaptation model, developed by Drs. Wingood and DiClemente, to facilitate the adaptation process. Study 2 is also a pilot test of the effectiveness of the adapted SiHLE intervention for this subgroup of non-responsive adolescents. The findings from the two studies in this application will make significant contributions to our understanding of adolescent sexual risk behavior and the development of effective HIV interventions which could modify the risk trajectory for HIV acquisition in hard-to-change adolescents.

Public Health Relevance

HIV prevention interventions tailored for African-American adolescent females who are non-responsive to sexual behavior risk-reduction interventions are urgently needed as these individuals are at especially high- risk for contracting HIV/STDs. The adoption of the adapted SiHLE intervention by other health departments and community-based AIDS service organizations has the potential to reach a broad audience and a population substantially impacted by the HIV epidemic.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Research Scientist Development Award - Research & Training (K01)
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Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
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Kamath, Susannah M Allison
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Emory University
Schools of Public Health
United States
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Hulland, Erin N; Brown, Jennifer L; Swartzendruber, Andrea L et al. (2015) The association between stress, coping, and sexual risk behaviors over 24 months among African-American female adolescents. Psychol Health Med 20:443-56
Brown, Jennifer L; Sales, Jessica M; DiClemente, Ralph J (2014) Combination HIV prevention interventions: the potential of integrated behavioral and biomedical approaches. Curr HIV/AIDS Rep 11:363-75
Swartzendruber, Andrea; Sales, Jessica M; Brown, Jennifer L et al. (2014) Correlates of incident Trichomonas vaginalis infections among African American female adolescents. Sex Transm Dis 41:240-5
Brown, Jennifer L; Young, April M; Sales, Jessica M et al. (2014) Impact of Abuse History on Adolescent African-American Women's Current HIV/STD-associated Behaviors and Psychosocial Mediators of HIV/STD Risk. J Aggress Maltreat Trauma 23:151-167
DiClemente, Ralph J; Davis, Teaniese L; Swartzendruber, Andrea et al. (2014) Efficacy of an HIV/STI sexual risk-reduction intervention for African American adolescent girls in juvenile detention centers: a randomized controlled trial. Women Health 54:726-49
Sales, Jessica McDermott; Monahan, Jennifer L; Brooks, Carolyn et al. (2014) Differences in sexual risk behaviors between lower and higher frequency alcohol-using African-American adolescent females. Curr HIV Res 12:276-81
Sales, Jessica M; Smearman, Erica L; Swartzendruber, Andrea et al. (2014) Socioeconomic-related risk and sexually transmitted infection among African-American adolescent females. J Adolesc Health 55:698-704
Swartzendruber, Andrea; Sales, Jessica M; Brown, Jennifer L et al. (2013) Predictors of repeat Chlamydia trachomatis and/or Neisseria gonorrhoeae infections among African-American adolescent women. Sex Transm Infect 89:76-82
DiClemente, Ralph J; Bradley, Erin; Davis, Teaniese L et al. (2013) Adoption and implementation of a computer-delivered HIV/STD risk-reduction intervention for African American adolescent females seeking services at county health departments: implementation optimization is urgently needed. J Acquir Immune Defic Syndr 63 Suppl 1:S66-71
Sales, Jessica M; Smearman, Erica L; Brody, Gene H et al. (2013) Factors associated with sexual arousal, sexual sensation seeking and sexual satisfaction among female African American adolescents. Sex Health 10:512-21

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