Most adults who suffer from a chronic illness are married or in an intimate relationship, yet the vast majority of behavioral interventions fail to address this relationship's impact or the effects of illness on the partner. Therefore, such interventions are not likely to be fully effective for many patients, and may even backfire. The purpose of this proposed K02 Independent Scientist Award (ISA) to Dr. Lynn Martire is to advance the development of couple-oriented interventions (CIs) for chronic illness that benefit both patients and spouses and also inform models of marriage and health. The focus of this award will be three chronic conditions that are the most deadly and costly of all health problems in the United States: cardiovascular disease, cancer, and diabetes. Dr. Martire's career development activities will address design, measurement, and analysis issues that are critical for the success of future CI research. The research activities of this ISA will add critical information to the literature on marriage and health, and inform the next generation of CIs, by focusing on how short-term processes that occur in the home environment affect health.
Aims #1 and 2 will examine daily processes in couples living with chronic illness, as well as individual and couple-level characteristics that moderate these processes, using dyadic diary data collected in studies of knee osteoarthritis and Type 2 diabetes.
Aim #3 is to collect pilot observational data on couples'health-related interactions in the home.
Aim #4 will apply findings from these and other projects to the development of an adaptive, cross-disease intervention for couples. The Candidate is uniquely poised to make significant advances in this area due to her research expertise in late-life chronic illness, family caregiving, and the effects of intervention on both patient and caregiver. Research and training activities will be facilitated by a team of Consultants who are leading experts in the areas of intimate relationships, health, longitudinal measurement and analysis, intervention development, and ecological momentary intervention. In addition, the Candidate has assembled a National Working Group of established researchers testing CIs for the three focal conditions of this ISA.

Public Health Relevance

Chronic illnesses account for 70% of all deaths in the United States and more than 75% of the nation's medical care costs. These conditions are most prevalent in middle-aged and older adults, and the majority of these individuals are married or in an intimate relationship. In order to contain escalating health care costs in the future, it is critical to identify strong behavioral approaches that target this relationship's impact on health.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Scientist Development Award - Research (K02)
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National Institute on Aging Initial Review Group (NIA)
Program Officer
Gerald, Melissa S
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Pennsylvania State University
Other Health Professions
Schools of Allied Health Profes
University Park
United States
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Martire, Lynn M; Wilson, Stephanie J; Small, Brent J et al. (2016) COMT and OPRM1 Genotype Associations with Daily Knee Pain Variability and Activity Induced Pain. Scand J Pain 10:6-12
Hemphill, Rachel C; Martire, Lynn M; Polenick, Courtney A et al. (2016) Spouse confidence and physical function among adults with osteoarthritis: The mediating role of spouse responses to pain. Health Psychol 35:1059-68
Luyster, Faith S; Dunbar-Jacob, Jacqueline; Aloia, Mark S et al. (2016) Patient and Partner Experiences With Obstructive Sleep Apnea and CPAP Treatment: A Qualitative Analysis. Behav Sleep Med 14:67-84
Polenick, Courtney A; Martire, Lynn M; Hemphill, Rachel C et al. (2015) Effects of change in arthritis severity on spouse well-being: The moderating role of relationship closeness. J Fam Psychol 29:331-8
Taylor, Briana J; Irish, Leah A; Martire, Lynn M et al. (2015) Avoidant Coping and Poor Sleep Efficiency in Dementia Caregivers. Psychosom Med 77:1050-7
Gere, Judith; Martire, Lynn M; Keefe, Francis J et al. (2014) Spouse confidence in self-efficacy for arthritis management predicts improved patient health. Ann Behav Med 48:337-46
Wilson, Stephanie J; Martire, Lynn M; Keefe, Francis J et al. (2013) Daily verbal and nonverbal expression of osteoarthritis pain and spouse responses. Pain 154:2045-53
Martire, Lynn M; Stephens, Mary Ann Parris; Mogle, Jacqueline et al. (2013) Daily spousal influence on physical activity in knee osteoarthritis. Ann Behav Med 45:213-23
Martire, Lynn M; Keefe, Francis J; Schulz, Richard et al. (2013) The impact of daily arthritis pain on spouse sleep. Pain 154:1725-31