This is an application for an Independent Scientist Award (K02) that would enable the PI to further develop his research on emotional and social impairment within schizophrenia. The career development plan will allow the PI to obtain training in affective and social neuroscience research that can then serve as the basis for additional translational research in the study and treatment of schizophrenia. This training will involve the following interrelated areas: developmental perspectives on peer relationship formation and socialization, developmental approaches to the understanding of individual differences in temperament and emotion, psychophysiological methods in the study of emotion, and social neuroscience approaches to the study of social behavior and emotion. These career development goals will be met through consultation, research activities, and collaborations with senior researchers in the areas of developmental psychology, basic emotion research, and social neuroscience. Classroom and technical training as well as attendance at scientific meetings and workshops will complement these consulting activities. The proposed didactic and career development activities are closely coupled with the research plan that is, in part, based on the PI's current funded research on anhedonia in schizophrenia and schizotypy (R01 MH512460). Ongoing and planned research will focus on understanding how emotion is altered in schizotypy and schizophrenia including how these emotional changes contribute to disturbances in affiliation and resulting social impairment. This research will span community samples involving schizophrenia-spectrum disorders as well as planned studies on schizophrenia. In sum, an Independent Scientist Award will provide the needed protected time for the PI to develop new skills in the study of emotion and social behavior from a basic science perspective. These new skills will be applied by the PI to future translational research aimed at understanding the profound emotional and social deficits occurring in schizophrenia and will have direct benefit to the development of future interventions in schizophrenia.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02MH079231-03
Application #
7789555
Study Section
Adult Psychopathology and Disorders of Aging Study Section (APDA)
Program Officer
Chavez, Mark
Project Start
2008-07-08
Project End
2013-03-31
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
3
Fiscal Year
2010
Total Cost
$126,360
Indirect Cost
Name
University of Maryland College Park
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
790934285
City
College Park
State
MD
Country
United States
Zip Code
20742
McCarthy, Julie M; Treadway, Michael T; Bennett, Melanie E et al. (2016) Inefficient effort allocation and negative symptoms in individuals with schizophrenia. Schizophr Res 170:278-84
Llerena, Katiah; Park, Stephanie G; McCarthy, Julie M et al. (2013) The Motivation and Pleasure Scale-Self-Report (MAP-SR): reliability and validity of a self-report measure of negative symptoms. Compr Psychiatry 54:568-74
Llerena, Katiah; Park, Stephanie G; Couture, Shannon M et al. (2012) Social anhedonia and affiliation: examining behavior and subjective reactions within a social interaction. Psychiatry Res 200:679-86
Park, Stephanie G; Llerena, Katiah; McCarthy, Julie M et al. (2012) Screening for negative symptoms: preliminary results from the self-report version of the Clinical Assessment Interview for Negative Symptoms. Schizophr Res 135:139-43
Cohen, Alex S; Couture, Shannon M; Blanchard, Jack J (2012) Neuropsychological functioning and social anhedonia: three-year follow-up data from a longitudinal community high risk study. J Psychiatr Res 46:898-904
Horan, William P; Kring, Ann M; Gur, Raquel E et al. (2011) Development and psychometric validation of the Clinical Assessment Interview for Negative Symptoms (CAINS). Schizophr Res 132:140-5
Couture, Shannon M; Blanchard, Jack J; Bennett, Melanie E (2011) Negative expectancy appraisals and defeatist performance beliefs and negative symptoms of schizophrenia. Psychiatry Res 189:43-8
Blanchard, Jack J; Collins, Lindsay M; Aghevli, Minu et al. (2011) Social anhedonia and schizotypy in a community sample: the Maryland longitudinal study of schizotypy. Schizophr Bull 37:587-602
Reise, Steven P; Horan, William P; Blanchard, Jack J (2011) The challenges of fitting an item response theory model to the Social Anhedonia Scale. J Pers Assess 93:213-24
Blanchard, Jack J; Kring, Ann M; Horan, William P et al. (2011) Toward the next generation of negative symptom assessments: the collaboration to advance negative symptom assessment in schizophrenia. Schizophr Bull 37:291-9

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