Abstract

I am applying for a second five-year Established Investigator Award to allow me to continue my cancer research agenda and to provide time for mentoring junior colleagues. The application seeks to document the degree to which the initial Award enabled me to have success in each of these areas, and the specific ways in which support for five additional years would be put to use. In terms of research, I propose to: 1) continue to develop and refine epidemiologic methods;2) assist colleagues in the conduct of molecular epidemiologic studies of endometrial and lung cancer;and 3) assess the influence of postmenopausal hormone therapy on the, risk of death from breast cancer. In terms of mentoring, I would continue the commitment I have made in the initial five years of K05 funding to mentoring junior faculty who are planning or engaged in studies of the epidemiology or clinical epidemiology of cancer. Based on my experience to date, these faculty will be located both within and outside of the University of Washington.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Scientist Award (K05)
Project #
5K05CA092002-09
Application #
8324691
Study Section
Subcommittee G - Education (NCI)
Program Officer
Perkins, Susan N
Project Start
2001-07-01
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
9
Fiscal Year
2012
Total Cost
$156,254
Indirect Cost
$11,574

  Institution

Name
University of Washington
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

O'Mara, Tracy A; Glubb, Dylan M; Amant, Frederic et al. (2018) Identification of nine new susceptibility loci for endometrial cancer. Nat Commun 9:3166
Jordan, Susan J; Na, Renhua; Johnatty, Sharon E et al. (2017) Breastfeeding and Endometrial Cancer Risk: An Analysis From the Epidemiology of Endometrial Cancer Consortium. Obstet Gynecol 129:1059-1067
Chen, Maxine M; O'Mara, Tracy A; Thompson, Deborah J et al. (2016) GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer. Hum Mol Genet 25:2612-2620
Machiela, Mitchell J; Zhou, Weiyin; Karlins, Eric et al. (2016) Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome. Nat Commun 7:11843
Felix, Ashley S; Gaudet, Mia M; La Vecchia, Carlo et al. (2015) Intrauterine devices and endometrial cancer risk: a pooled analysis of the Epidemiology of Endometrial Cancer Consortium. Int J Cancer 136:E410-22
Cote, Michele L; Alhajj, Tala; Ruterbusch, Julie J et al. (2015) Risk factors for endometrial cancer in black and white women: a pooled analysis from the Epidemiology of Endometrial Cancer Consortium (E2C2). Cancer Causes Control 26:287-296
Pocobelli, Gaia; Weiss, Noel S (2015) Breast cancer mortality in relation to receipt of screening mammography: a case-control study in Saskatchewan, Canada. Cancer Causes Control 26:231-237
Weiss, Noel S (2015) Commentary: Cohort studies of the efficacy of screening for cancer. Epidemiology 26:362-4
Pocobelli, Gaia; Newcomb, Polly A; Li, Christopher I et al. (2014) Fatal breast cancer risk in relation to use of unopposed estrogen and combined hormone therapy. Breast Cancer Res Treat 145:439-47
Rustagi, Alison S; Kamineni, Aruna; Weinmann, Sheila et al. (2014) Cervical screening and cervical cancer death among older women: a population-based, case-control study. Am J Epidemiol 179:1107-14

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