This is a first submission of a NIDA Senior Scientist Research and Mentorship (K05) award application. Funding for this grant would begin at the end of the candidate's second NIDA K24 award, """"""""Mentoring in Drug Abuse Neuroimaging"""""""" (DA015116). The major aims of this application would be to relieve the PI of substantial clinical responsibilities in order to have more protected time for research (25% effort);mentoring (25% effort);and infrastructure building (25% effort).
The Specific Aims of this K05 application are as follows: 1. To actively participate in independent and collaborative R01 research projects. This research should require 25% effort, and initially will consist of funded research that is supported by grants: 5R01DA024070, Longitudinal neuroimaging of methamphetamine-dependent adolescents (PI: Renshaw and Lyoo, 9/08-6/13); 1R01DA025065, Sex/gender and nicotine addiction: Hormones behavior and neuroimaging (PI: Mello and Renshaw, 3/10-12/14);5R01DA027135, Citicoline treatment of methamphetamine dependence (PI: Renshaw, 8/09-7/11);and 5R01MH58681, MRI/MRSI studies of bipolar treatment response (PI: Renshaw, 9/99-6/11) in collaboration with my trainees. 2. To continue spending time working with young investigators. My on-going mentoring activities for my fourteen current mentees will require 25% of my effort, which will allow me to meet or speak with each of my current and future trainees on a weekly basis. 3. To engage in building the clinical drug abuse research infrastructure at the University of Utah. In addition to a recently funded research dedicated scanner, I would like to work toward Translational Drug Abuse Research Training (T32);Research Education (R25);and Center (P20) grant submissions over the five year period funding. These projects will also require approximately 25% of my effort and, if successful, will serve as resources that will greatly expand our ability to train younger investigators. !

Public Health Relevance

Project Narrative Drug abuse remains a major public health problem in the United States. This grant, if funded, would provide 75% protected time for clinical drug abuse research (25%), mentoring of younger scientists with interest in drug abuse research (25%), and further development of a drug abuse research infrastructure at the University of Utah (25%). New research will focus on methamphetamine dependence and drug abuse by youth, both of which are pressing local problems in Salt Lake County.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Scientist Award (K05)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Grant, Steven J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Utah
Schools of Medicine
Salt Lake City
United States
Zip Code
Jeong, Bum Seok; Han, Doug Hyun; Kim, Sun Mi et al. (2016) White matter connectivity and Internet gaming disorder. Addict Biol 21:732-42
Yildiz, Ay?egül; Aydin, Burç; Gökmen, Necati et al. (2016) Antimanic Treatment With Tamoxifen Affects Brain Chemistry: A Double-Blind, Placebo-Controlled Proton Magnetic Resonance Spectroscopy Study. Biol Psychiatry Cogn Neurosci Neuroimaging 1:125-131
Lyoo, I K; Yoon, S; Kim, T S et al. (2015) Predisposition to and effects of methamphetamine use on the adolescent brain. Mol Psychiatry 20:1516-24
Sung, Young-Hoon; Yurgelun-Todd, Deborah A; Kondo, Douglas G et al. (2015) Gender differences in the effect of tobacco use on brain phosphocreatine levels in methamphetamine-dependent subjects. Am J Drug Alcohol Abuse 41:281-9
Bakian, Amanda V; Huber, Rebekah S; Coon, Hilary et al. (2015) Bakian et al. respond to ""Assessing air pollution and suicide risk"". Am J Epidemiol 181:309-10
Choi, Jae Won; Han, Doug Hyun; Kang, Kyung Doo et al. (2015) Aerobic exercise and attention deficit hyperactivity disorder: brain research. Med Sci Sports Exerc 47:33-9
Bogdanov, Volodymyr B; Viganò, Alessandro; Noirhomme, Quentin et al. (2015) Cerebral responses and role of the prefrontal cortex in conditioned pain modulation: an fMRI study in healthy subjects. Behav Brain Res 281:187-98
Huber, Rebekah S; Kim, Tae-Suk; Kim, Namkug et al. (2015) Association Between Altitude and Regional Variation of ADHD in Youth. J Atten Disord :
Nallathamby, Prakash D; Mortensen, Ninell P; Palko, Heather A et al. (2015) New surface radiolabeling schemes of super paramagnetic iron oxide nanoparticles (SPIONs) for biodistribution studies. Nanoscale 7:6545-55
Hellem, Tracy L; Lundberg, Kelly J; Renshaw, Perry F (2015) A review of treatment options for co-occurring methamphetamine use disorders and depression. J Addict Nurs 26:14-23; quiz E1

Showing the most recent 10 out of 97 publications