The proposed research focus is psychotic disorders associated with aging. During the award term, a study of visual hallucinations (VH) in Alzheimer's disease (AD) will be conducted, examining correlates to VH including possible neuroanatomic pathology. It is predicted that decreased visual acuity, severity of visual agnosia, history of hearing or visual disorder, female sex, older age, number of medications and temporal and occipital cortical atrophy will associate significantly with VH. This is the first study in my planned program of research to examine psychotic symptoms in AD and other disorders of aging, making linkages of such symptoms to pathophysiology (visual system, brain) where possible.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07MH001199-04
Application #
2609423
Study Section
Special Emphasis Panel (SRCM (01))
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1997-12-24
Budget End
1998-11-30
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Virginia
Department
Psychiatry
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Turnbull, Quentin; Wolf, Andrew M D; Holroyd, Suzanne (2003) Attitudes of elderly subjects toward ""truth telling"" for the diagnosis of Alzheimer's disease. J Geriatr Psychiatry Neurol 16:90-3
Holroyd, Suzanne; Turnbull, Quentin; Wolf, Andrew M (2002) What are patients and their families told about the diagnosis of dementia? Results of a family survey. Int J Geriatr Psychiatry 17:218-21
Holroyd, S; Currie, L; Wooten, G F (2001) Prospective study of hallucinations and delusions in Parkinson's disease. J Neurol Neurosurg Psychiatry 70:734-8
Holroyd, S; Shepherd, M L; Downs 3rd, J H (2000) Occipital atrophy is associated with visual hallucinations in Alzheimer's disease. J Neuropsychiatry Clin Neurosci 12:25-8
Webster, R; Holroyd, S (2000) Prevalence of psychotic symptoms in delirium. Psychosomatics 41:519-22
Holroyd, S; Duryee, J J (1997) Differences in geriatric psychiatry outpatients with early- vs late-onset depression. Int J Geriatr Psychiatry 12:1100-6
Holroyd, S; Duryee, J J (1997) Characteristics of persons utilizing a geriatric psychiatry outpatient clinic. J Geriatr Psychiatry Neurol 10:136-41
Holroyd, S; Duryee, J J (1997) Substance use disorders in a geriatric psychiatry outpatient clinic: prevalence and epidemiologic characteristics. J Nerv Ment Dis 185:627-32
Holroyd, S; Snustad, D G; Chalifoux, Z L (1996) Attitudes of older adults' on being told the diagnosis of Alzheimer's disease. J Am Geriatr Soc 44:400-3
Holroyd, S (1996) Visual hallucinations in a geriatric psychiatry clinic: prevalence and associated diagnoses. J Geriatr Psychiatry Neurol 9:171-5