Dr. Morrison's interest in quality of life issues at the end-of-life has led him to focus on palliative care and geriatrics. Merging these two areas, his clinical and research work suggest that pain symptoms tend to be overlooked in patients presenting with dementia/delirium. Dr. Morrison's long-term objectives are to promote understanding of this issue and to enhance the quality of life of older patients through improved pain and symptom management. The overall objective of the research project is to examine the management of pain in hip fracture patients and the inter-related problem of delirium.
The specific aims are to: determine the incidence and prevalence of pain and delirium in patients with hip fracture; describe the management of pain and delirium; identify risk factors for the development of delirium and for inadequate pain management; examine the relationship between delirium and pain on select patient outcome variables; and develop strategies and interventions to improve the management of delirium and pain. Patients entering the Mount Sinai Health System presenting with a hip fracture will be studied. All patients will be assessed daily through the fifth hospital or third full post-operative day and thereafter every other day through the ninth hospital day for the severity of their pain and for delirium. Information will be collected on specific processes of care that are used during the treatment course of these patients with particular attention to those processes that could lead to the development of pain or delirium and those directed at the management of these two conditions by concurrently following the course of the patients and by reviewing medical records. Patients will be followed longitudinally through their hospitalization and at 2 and 6 months with assessments of pain, functional status, morbidity, and mortality. In the final half of the five year project, the data collected from the initial phase of this proposal will be used to plan and test two interventions at the Mount Sinai Hospital. The first intervention will be directed at improving pain management. The second intervention will be randomized controlled trial evaluating the pharmacologic management of delirium. Dr. Morrison will engage in a number of educational activities in order to enhance his research and statistical analysis skills.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AG000833-03
Application #
6167928
Study Section
Special Emphasis Panel (ZAG1-DAG-9 (J5))
Program Officer
Premen, Andre J
Project Start
1998-07-01
Project End
2003-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
3
Fiscal Year
2000
Total Cost
$104,382
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Other Health Professions
Type
Schools of Medicine
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029
Nelson, Judith E; Meier, Diane E; Litke, Ann et al. (2004) The symptom burden of chronic critical illness. Crit Care Med 32:1527-34
Orosz, Gretchen M; Magaziner, Jay; Hannan, Edward L et al. (2004) Association of timing of surgery for hip fracture and patient outcomes. JAMA 291:1738-43
Meier, Diane E; Thar, William; Jordan, Ashby et al. (2004) Integrating case management and palliative care. J Palliat Med 7:119-34
Resnick, Seth; Morrison, R Sean (2004) Physicians' perceptions of procedural pain and discomfort. J Palliat Med 7:646-51
Morrison, R Sean; Meier, Diane E (2004) High rates of advance care planning in New York City's elderly population. Arch Intern Med 164:2421-6
Maroney, Catherine L; Litke, Ann; Fischberg, Daniel et al. (2004) Acceptability of severe pain among hospitalized adults. J Palliat Med 7:443-50
Meier, Diane E; Emmons, Carol-Ann; Litke, Ann et al. (2003) Characteristics of patients requesting and receiving physician-assisted death. Arch Intern Med 163:1537-42
Morrison, R Sean; Magaziner, Jay; McLaughlin, Mary Ann et al. (2003) The impact of post-operative pain on outcomes following hip fracture. Pain 103:303-11
Morrison, R Sean; Magaziner, Jay; Gilbert, Marvin et al. (2003) Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci 58:76-81
Gruber-Baldini, Ann L; Zimmerman, Sheryl; Morrison, R Sean et al. (2003) Cognitive impairment in hip fracture patients: timing of detection and longitudinal follow-up. J Am Geriatr Soc 51:1227-36

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