Dr. Jennifer Tjia, a Geriatrics Fellow at the University of Pennsylvania, is dedicated to a career in Geriatric Health Services Research. Dr. Tjia's goal is to develop a multidisciplinary research program to (1) understand the effect of state & federal prescription drug policies on elder health outcomes and health service use and (2) understand the predictors of medication uptake and adherence among older adults. This Mentored Clinical Scientist Career Development Award will provide the means to take two important steps toward this goal. First, it will allow for additional intensive mentored education and training in public policy research, health economics, and advanced statistics that will augment previous rigorous training in epidemiology, biostatistics, and clinical medicine. Second, it will support the development of an original clinical research program using rigorous epidemiologic and econometric methods to examine the impact of prescription drug coverage on health outcomes. As new prescription drugs contribute to rising health care costs and the promise of improved health, it is important to understand how prescription drug insurance affects the health and medical service utilization of older adults. Although some policymakers argue that the provision of a pharmacy benefit may reduce costs through reduced health service utilization and improved health, evidence to support this assertion is lacking. The candidate proposes two complementary studies at both the national and state levels to address the important, unanswered questions about medication access by older adults. Study One is a national-level observational cohort study using data from the Medicare Current Beneficiary Survey (MCBS) to examine the effect of drug coverage on the incidence of adverse events and medication persistence. Study Two is a health policy natural experiment using North Carolina Medicaid claims to measure the effect of a new drug benefit program on adverse events and state health care expenditures. This two-part research program will triangulate on the nexus of issues central to understanding the effect of prescription drug policy on elder health outcomes and form the foundation for the candidate's transition to an independent investigator in Geriatric Health Services Research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AG021527-02
Application #
6887742
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Haaga, John G
Project Start
2004-07-01
Project End
2009-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
2
Fiscal Year
2005
Total Cost
$116,581
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Tjia, Jennifer; Cutrona, Sarah L; Peterson, Daniel et al. (2014) Statin discontinuation in nursing home residents with advanced dementia. J Am Geriatr Soc 62:2095-101
Tjia, Jennifer; Mazor, Kathleen M; Field, Terry et al. (2011) Predicting nursing home adherence to a clinical trial intervention: lessons for the conduct of cluster randomized trials. J Am Geriatr Soc 59:2332-6
Tjia, Jennifer; Rothman, Margaret R; Kiely, Dan K et al. (2010) Daily medication use in nursing home residents with advanced dementia. J Am Geriatr Soc 58:880-8
Givens, Jane L; Tjia, Jennifer; Zhou, Chao et al. (2010) Racial and ethnic differences in hospice use among patients with heart failure. Arch Intern Med 170:427-32
Chen, Yong; Briesacher, Becky A; Field, Terry S et al. (2010) Unexplained variation across US nursing homes in antipsychotic prescribing rates. Arch Intern Med 170:89-95
Tjia, Jennifer; Briesacher, Becky; Xie, Dawei et al. (2010) Disparities in combination drug therapy use in older adults with coronary heart disease: a cross-sectional time-series in a nationally representative US sample. Drugs Aging 27:149-58
Tjia, Jennifer; Bonner, Alice; Briesacher, Becky A et al. (2009) Medication discrepancies upon hospital to skilled nursing facility transitions. J Gen Intern Med 24:630-5
Tjia, Jennifer; Mazor, Kathleen M; Field, Terry et al. (2009) Nurse-physician communication in the long-term care setting: perceived barriers and impact on patient safety. J Patient Saf 5:145-52
Huang, Jason H; Zager, Eric L; Zhang, Jun et al. (2008) Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation. Laboratory investigation. J Neurosurg 108:343-7
Tjia, Jennifer; Briesacher, Becky A; Soumerai, Stephen B et al. (2008) Medicare beneficiaries and free prescription drug samples: a national survey. J Gen Intern Med 23:709-14

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