Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08DK002315-02
Application #
2134213
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1995-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Ehrmann, David A (2005) Polycystic ovary syndrome. N Engl J Med 352:1223-36
Ehrmann, David A; Breda, Elena; Corcoran, Matthew C et al. (2004) Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome. Am J Physiol Endocrinol Metab 287:E241-6
Ehrmann, D A; Breda, E; Cavaghan, M K et al. (2002) Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance. Diabetologia 45:509-17
Hara, Manami; Alcoser, Sergio Y; Qaadir, Arshia et al. (2002) Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene. J Clin Endocrinol Metab 87:772-5
Colilla, S; Cox, N J; Ehrmann, D A (2001) Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives. J Clin Endocrinol Metab 86:2027-31
Cavaghan, M K; Ehrmann, D A; Polonsky, K S (2000) Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest 106:329-33
Ehrmann, D A (2000) Glucose intolerance in the polycystic ovary syndrome: role of the pancreatic beta-cell. J Pediatr Endocrinol Metab 13 Suppl 5:1299-301
Ehrmann, D A; Barnes, R B; Rosenfield, R L et al. (1999) Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 22:141-6
Cavaghan, M K; Ehrmann, D A; Byrne, M M et al. (1997) Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. J Clin Invest 100:530-7
Ehrmann, D A; Cavaghan, M K; Imperial, J et al. (1997) Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 82:524-30

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