Oxidant-Induced Macrophage Arachidonic Acid Metabolism

Sporn, Peter H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 7K08HL002407-02
• Application #: 3082792
• Study Section: Research Manpower Review Committee (MR)
• Project Start: 1991-08-16
• Project End: 1995-07-31
• Budget Start: 1991-08-16
• Budget End: 1991-08-31
• Support Year: 2
• Fiscal Year: 1990

Institution

• Name: Northwestern University at Chicago
• Type: Schools of Medicine
• DUNS #: 005436803
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60611

Publications

Sporn, P H; Lestrud, S O; Fries, F P et al. (1997) Keratinocyte growth factor increases LTC4 synthesis and expression of flap in cultured rat alveolar type II cells. Adv Exp Med Biol 433:395-8

Coffey, M; Peters-Golden, M; Fantone 3rd, J C et al. (1992) Membrane association of active 5-lipoxygenase in resting cells. Evidence for novel regulation of the enzyme in the rat alveolar macrophage. J Biol Chem 267:570-6

Sporn, P H; Marshall, T M; Peters-Golden, M (1992) Hydrogen peroxide increases the availability of arachidonic acid for oxidative metabolism by inhibiting acylation into phospholipids in the alveolar macrophage. Am J Respir Cell Mol Biol 7:307-16