Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
7K08HL003556-03
Application #
2724176
Study Section
Special Emphasis Panel (ZHL1-CSR-Y (M1))
Project Start
1996-08-15
Project End
2001-07-31
Budget Start
1997-10-15
Budget End
1998-07-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Georgetown University
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Freedman, J E; Keaney Jr, J F (2001) Vitamin E inhibition of platelet aggregation is independent of antioxidant activity. J Nutr 131:374S-7S
Freedman, J E; Parker 3rd, C; Li, L et al. (2001) Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation 103:2792-8
Parker 3rd, C; Vita, J A; Freedman, J E (2001) Soluble adhesion molecules and unstable coronary artery disease. Atherosclerosis 156:417-24
Keaney Jr, J F; Simon, D I; Freedman, J E (1999) Vitamin E and vascular homeostasis: implications for atherosclerosis. FASEB J 13:965-75
Freedman, J E; Sauter, R; Battinelli, E M et al. (1999) Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circ Res 84:1416-21
Freedman, J E; Ting, B; Hankin, B et al. (1998) Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes. Circulation 98:1481-6
Freedman, J E; Loscalzo, J; Barnard, M R et al. (1997) Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest 100:350-6