? The care """"""""of critically ill patients is a common, expensive, and growing part of American medicine. Some hospitals provide higher quality care to these patients than do other hospitals. Every year approximately 10,000 patients die from acute myocardial infarction who might have been saved had they been at a higher performing hospital. Similarly large numbers of patients die potentially avoidable deaths after mechanical ventilation. Given these large variations between hospitals in the quality of their care, there is growing interest in developing a formal system to transfer patients to higher quality hospitals. While there are calls for a formal system for transferring patients, an unplanned system has already evolved for the transfer of critically ill patients. We know critical care transfers are common, but we know very little abput the network over which they are transferred. In particular, we do not know whether the network directs patients towards higher quality hospitals. The global hypothesis of this proposal is that the critical care transfer network is a coherent structure, not just an aggregation of random processes. This structure, we hypothesize, is directly related to hospital organizational characteristics, impacts patient outcomes, and is amenable to intervention. We will perform three Specific Aims. First, we will map and characterize the network structure. Second, we will examine the association between a hospital's centrality in the network - that is, the degree to which the network moves patients towards to the hospital - and hospital organizational characteristics and capabilities. Third, we will determine the relationship between a hospital's network centrality and outcomes of its patients: We will use as our model system 30-day mortality after one of the most common disease processes requiring critical care: acute myocardial infarction. Data for this project will be derived primarily from the Medicare claims. This research is directly relevant to the goal of providing high quality care to patients with acute illness, particularly acute cardiac and pulmonary derangements. This proposal investigates whether the existing network of critical care transfers can be used as a foundation to improve the care of patients by moving patients to hospitals that provide better care. (End of Abstract) ? ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08HL091249-01
Application #
7357629
Study Section
Special Emphasis Panel (ZHL1-CSR-X (O1))
Program Officer
Cooper, Lawton S
Project Start
2008-09-19
Project End
2013-06-30
Budget Start
2008-09-19
Budget End
2009-06-30
Support Year
1
Fiscal Year
2008
Total Cost
$132,163
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Sauser Zachrison, Kori; Iwashyna, Theodore J; Gebremariam, Achamyeleh et al. (2016) Can longitudinal generalized estimating equation models distinguish network influence and homophily? An agent-based modeling approach to measurement characteristics. BMC Med Res Methodol 16:174
Govindan, Sushant; Iwashyna, Theodore J; Odden, Andrew et al. (2015) Mobilization in severe sepsis: an integrative review. J Hosp Med 10:54-9
Miller, Melissa A; Govindan, Sushant; Watson, Sam R et al. (2015) ABCDE, but in that order? A cross-sectional survey of Michigan intensive care unit sedation, delirium, and early mobility practices. Ann Am Thorac Soc 12:1066-71
Levine, Deborah A; Davydow, Dimitry S; Hough, Catherine L et al. (2014) Functional disability and cognitive impairment after hospitalization for myocardial infarction and stroke. Circ Cardiovasc Qual Outcomes 7:863-71
Davydow, Dimitry S; Hough, Catherine L; Zivin, Kara et al. (2014) Depression and risk of hospitalization for pneumonia in a cohort study of older Americans. J Psychosom Res 77:528-34
Lomi, Alessandro; Mascia, Daniele; Vu, Duy Quang et al. (2014) Quality of care and interhospital collaboration: a study of patient transfers in Italy. Med Care 52:407-14
Govindan, Sushant; Iwashyna, Theodore J; Watson, Sam R et al. (2014) Issues of survivorship are rarely addressed during intensive care unit stays. Baseline results from a statewide quality improvement collaborative. Ann Am Thorac Soc 11:587-91
Iwashyna, Theodore J; Odden, Andrew; Rohde, Jeffrey et al. (2014) Identifying patients with severe sepsis using administrative claims: patient-level validation of the angus implementation of the international consensus conference definition of severe sepsis. Med Care 52:e39-43
Davydow, Dimitry S; Zivin, Kara; Katon, Wayne J et al. (2014) Neuropsychiatric disorders and potentially preventable hospitalizations in a prospective cohort study of older Americans. J Gen Intern Med 29:1362-71
Prescott, Hallie C; Langa, Kenneth M; Liu, Vincent et al. (2014) Increased 1-year healthcare use in survivors of severe sepsis. Am J Respir Crit Care Med 190:62-9

Showing the most recent 10 out of 59 publications