Accomplishing advancements in vision science requires clinician researchers with training that spans many disciplines. The Vision Clinical Scientist Program at the University of Pennsylvania is designed to prepare clinician scientists to identify and prioritize important questions in their field, formulate a comprehensive approach to address the questions, and lead the efforts of a research team to provide answers. The Penn Vision Clinical Scientist Program is centered in the Department of Ophthalmology in the School of Medicine. The program takes advantage of established educational programs within the university, the concentration of strong basic science, translational research, and patient-oriented research programs ongoing within the Department of Ophthalmology, and the breadth of expertise available through Penn's interdisciplinary institutes and centers. Scholars have access to formal educational programs and applied research experiences in a vast an^ay of areas such as clinical epidemiology, single-center and multicenter clinical trials, health services research, bioethics, genetics, molecular biology, and neuroscience. Established investigators in basic science, translational research, and patient-oriented research serve as mentors to guide choices by scholars in educational programs and research projects. Although each program has a didactic training component and a component of supervised research with increasing independence, the specific content of each program is custom built for each scholar. Mentors advise scholars on activities necessary for professional development, collaboration among investigators, and developing long-term research programs. Upon completion of the program, scholars are well-prepared to perform productive and successful independent research.

Public Health Relevance

People with training and experience in preventing and treating eye disease, who are also skilled at doing research, are able to identify important problems in eye care and design the research projects needed to resolve the problems. The Penn Vision Clinical Scientist Program provides the resources necessary for such people to be successful.

National Institute of Health (NIH)
National Eye Institute (NEI)
Physician Scientist Award (Program) (PSA) (K12)
Project #
Application #
Study Section
Special Emphasis Panel (ZEY1-VSN (10))
Program Officer
Agarwal, Neeraj
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Pennsylvania
Schools of Medicine
United States
Zip Code
VanderBeek, Brian L; Shah, Neepa; Parikh, Purak C et al. (2016) Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. PLoS One 11:e0149450
Hunter 3rd, Allan A; Smit-McBride, Zeljka; Anderson, Rachel et al. (2016) GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration. Curr Eye Res 41:410-6
Bunya, Vatinee Y; Bhosai, Satasuk Joy; Heidenreich, Ana Maria et al. (2016) Association of Dry Eye Tests With Extraocular Signs Among 3514 Participants in the Sjögren's Syndrome International Registry. Am J Ophthalmol 172:87-93
Fuerst, Nicole M; Serrano, Leona; Han, Grace et al. (2016) Detailed functional and structural phenotype of Bietti crystalline dystrophy associated with mutations in CYP4V2 complicated by choroidal neovascularization. Ophthalmic Genet 37:445-452
Aleman, Tomas S; Han, Grace; Serrano, Leona W et al. (2016) Natural History of the Central Structural Abnormalities in Choroideremia: A Prospective Cross-Sectional Study. Ophthalmology :
Sandhu, Harpal Singh; Brucker, Alexander J; Ma, Liyuan et al. (2016) Oral Fluoroquinolones and the Risk of Uveitis. JAMA Ophthalmol 134:38-43
Binenbaum, Gil; Chen, Wendy; Huang, Jiayan et al. (2016) The natural history of retinal hemorrhage in pediatric head trauma. J AAPOS 20:131-5
Rose-Nussbaumer, Jennifer; Lietman, Thomas M; Shiboski, Caroline H et al. (2015) Inter-grader Agreement of the Ocular Staining Score in the Sjögren's International Clinical Collaborative Alliance (SICCA) Registry. Am J Ophthalmol 160:1150-1153.e3
Ghodasra, Devon H; Katowitz, James A; Liu, Grant T et al. (2015) Indirect internal carotid-cavernous fistula in infancy. J Pediatr Ophthalmol Strabismus 52 Online:e11-3
Bunya, Vatinee Y; Fuerst, Nicole M; Pistilli, Maxwell et al. (2015) Variability of Tear Osmolarity in Patients With Dry Eye. JAMA Ophthalmol 133:662-7

Showing the most recent 10 out of 60 publications