? UCSF IRACDA Scholars Program The need for increased representation of a diverse workforce in biomedical research at the academic level is clear and well-documented. This renewal application requests resources to continue our four-year Scholars training program at the University of California, San Francisco (UCSF) in partnership with San Francisco State University (SFSU). The goal of the program, which began in 2007, is to increase the number of highly trained, successfully funded and sustainable research scientists, who will perform high level laboratory and teaching and increase the diversity of younger trainees in biomedical research careers to ultimately improve our understanding of health-related science. To this end, UCSF has partnered with SFSU to build a program that provides comprehensive science and teaching training for mentoring Ph.D. scholars who are committed to an academic career and impacting underserved minority trainees. The key elements of our training program are (1) a mentored research experience, (2) a mentored teaching experience at SFSU, (3) monthly career development workshops, (4) interdisciplinary scientific experiences and (5) continuing review and evaluation. The centerpiece of the program is the 4-years of training, with the initial three years covered by the training grant and the last year covered by the PI funds or Independent Development Awards. The majority of this training (75%) is devoted to intense research training in basic laboratory science with the remaining training devoted to teaching experiences at the SFSU campus and mentoring experiences with undergraduate underrepresented students from SFSU. Our exceptionally well- qualified faculty and teaching mentors have committed their support to our IRACDA scholars. Internal and external Advisors as well as periodic formal evaluations will be a critical part of continued excellence and achievement of stated goals of the Program. Each Scholar is expected to interact with a team of at least three Faculty Research Mentors and two Teaching Mentors during their training; meeting on a regular basis to assist him/her in setting, and then monitoring training and career goals. Our program has a strong track history of recruiting exceptional Scholars representing a diverse background. Of the 35 current and past scholars, nearly 90% are URMs. Of the 21 Scholars who have completed their training at UCSF, they have produced an average of 3.4 peer- review publications (0-9 range), and over 50% have assumed academic positions, with 80% of these at R1/R3 Research Institutions (Vanderbilt, UCSD, UCSF, U of Arkansas, Duke, Georgetown, SFSU and SJSU). We believe the Program's strong outcomes data, the collaborative research-intensive training environment at UCSF, and the well-established and fruitful interactions between UCSF and SFSU provide compelling rationale for renewing and expanding this unique training opportunity to train and diversify the next generation of leaders in biomedical science.

Public Health Relevance

? UCSF IRACDA Scholars Program To improve the technical and scientific competitiveness of our nation, efforts must be made to increase participating scientists and engineers from underrepresented minority (URM) groups. The UCSF IRACDA Scholars Program addresses this challenge by training highly motivated postdoctoral scholars for academic faculty careers in biomedical research. These UCSF IRACDA Scholars, many of who come from underrepresented groups, are then asked to teach, mentor and inspire undergraduate URM students at our partner institution, San Francisco State University so that they can successfully enter scientific career pathways.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
2K12GM081266-11
Application #
9354207
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Salazar, Desiree Lynn
Project Start
2007-08-03
Project End
2022-07-31
Budget Start
2017-08-01
Budget End
2018-07-31
Support Year
11
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Pharmacology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118
Udeochu, Joe; Sayed, Faten A; Gan, Li (2018) TREM2 and Amyloid Beta: A Love-Hate Relationship. Neuron 97:991-993
Laurie, Matthew T; White, Corin V; Retallack, Hanna et al. (2018) Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris. MBio 9:
Garcia 3rd, Galo; Raleigh, David R; Reiter, Jeremy F (2018) How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In. Curr Biol 28:R421-R434
Monkkonen, Teresa; Debnath, Jayanta (2018) Inflammatory signaling cascades and autophagy in cancer. Autophagy 14:190-198
Publicover, Jean; Gaggar, Anuj; Jespersen, Jillian M et al. (2018) An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Sci Transl Med 10:
Langelier, Charles; Zinter, Matt S; Kalantar, Katrina et al. (2018) Metagenomic Sequencing Detects Respiratory Pathogens in Hematopoietic Cellular Transplant Patients. Am J Respir Crit Care Med 197:524-528
Zeiger, Andrew M; White, Marquitta J; Eng, Celeste et al. (2018) Genetic Determinants of Telomere Length in African American Youth. Sci Rep 8:13265
Mayoral, Sonia R; Etxeberria, Ainhoa; Shen, Yun-An A et al. (2018) Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber. Cell Rep 25:544-550.e3
Mak, Angel C Y; White, Marquitta J; Eckalbar, Walter L et al. (2018) Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med 197:1552-1564
de Jesus Cortez, Felipe; Nguyen, Phuong; Truillet, Charles et al. (2017) Development of 5N-Bicalutamide, a High-Affinity Reversible Covalent Antiandrogen. ACS Chem Biol 12:2934-2939

Showing the most recent 10 out of 66 publications