The principal mission of the University of California, San Francisco (UCSF) Women's Reproductive Health Research (WRHR) Career Development Center is to promote health and prevent disease in women by expanding the pool of well-trained, imaginative, productive investigators in the field of women's reproductive health. It is our purpose to recruit, mentor, and prepare outstanding candidates to acquire and refine the skills needed to reach this goal. As one of the original institutions awarded a WRHR Center, we have established an infrastructure, curriculum, and Scholar mentoring system to meet the challenge of training the next generation of academic Obstetrician-Gynecologists. Based on the successes of two cohorts of Scholars over the past 10 years, we propose a structured Scholar program of sufficient duration, relevant didactic education, and immersion into a vibrant, intellectually challenging, research community, leading to academic independence. The education of our Scholars will be further enriched by our collaboration with the UCSF Clinical &Translational Science Institute (CTSI), which provides ongoing infrastructure, resource, training and research opportunities. We have learned that appropriate scientific and academic mentoring is mandatory during the initial years of a junior faculty appointment, helping the individual to overcome hurdles that impede a rewarding, successful and productive academic career. Scholars will be recruited to pursue two general areas, biomedical (laboratory-based) research and clinical research, in reproductive science. In addition, two general pathways (I and II) have been established to guide relatively inexperienced (Track I) and more senior Scholars (Track II), respectively. Translational research, a burgeoning focus within our department that has benefited from long-standing multidisciplinary partnerships, will be gained through participation in studies bridging the biomedically and clinically oriented projects. We are committed to nurturing a cadre of UCSF WRHR Scholars who will improve the health status of women by conducting important discovery, expanding knowledge, and testing innovations for the prevention, diagnosis and treatment of reproductive disorders. Through our proposed mentoring program, we anticipate that our Scholars will be independent investigators and future leaders of women's reproductive health research nationally and internationally.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Physician Scientist Award (Program) (PSA) (K12)
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Application #
Study Section
Special Emphasis Panel (ZHD1-DSR-L (14))
Program Officer
Lamar, Charisee A
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University of California San Francisco
Obstetrics & Gynecology
Schools of Medicine
San Francisco
United States
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Washburn, Erin E; Sparks, Teresa N; Gosnell, Kristen A et al. (2017) Polyhydramnios Affecting a Recipient-like Twin: Risk of Progression to Twin-Twin Transfusion Syndrome and Outcomes. Am J Perinatol :
Cakmak, Hakan; Franciosi, Federica; Zamah, A Musa et al. (2016) Dynamic secretion during meiotic reentry integrates the function of the oocyte and cumulus cells. Proc Natl Acad Sci U S A 113:2424-9
Greenwald, Sally R; Gonzalez, Juan M; Goldstein, Ruth G et al. (2016) Reply. Am J Obstet Gynecol 214:415-6
Esakoff, Tania F; Cheng, Yvonne W; Snowden, Jonathan M et al. (2015) Velamentous cord insertion: is it associated with adverse perinatal outcomes? J Matern Fetal Neonatal Med 28:409-12
Snowden, Jonathan M; Cheng, Yvonne W; Emeis, Cathy L et al. (2015) The impact of hospital obstetric volume on maternal outcomes in term, non-low-birthweight pregnancies. Am J Obstet Gynecol 212:380.e1-9
Piltonen, T T; Chen, J C; Khatun, M et al. (2015) Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro. Hum Reprod 30:1203-15
Greenwald, Sally R; Gonzalez, Juan M; Goldstein, Ruth G et al. (2015) Asymptomatic uterine dehiscence in a second-trimester twin pregnancy. Am J Obstet Gynecol 213:590.e1-2
Lewkowitz, Adam Korrick; Nakagawa, Sanae; Thiet, Mari-Paule et al. (2015) Effect of stage of initial labor dystocia on vaginal birth after cesarean success. Am J Obstet Gynecol 213:861.e1-5
Rosenstein, Melissa G; Nijagal, Malini; Nakagawa, Sanae et al. (2015) The Association of Expanded Access to a Collaborative Midwifery and Laborist Model With Cesarean Delivery Rates. Obstet Gynecol 126:716-23
Nijagal, Malini Anand; Kuppermann, Miriam; Nakagawa, Sanae et al. (2015) Two practice models in one labor and delivery unit: association with cesarean delivery rates. Am J Obstet Gynecol 212:491.e1-8

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