This competing renewal application for the Penn Women's Reproductive Health Research (WRHR) Career Development Center seeks continued support for training and mentorship for obstetrician-gynecologists with the goal of cultivating a cadre of independent scholars in women's health, emphasizing multidisciplinary approaches. The program will continue to have a steady state of 3 WRHR Scholars. The Penn WRHR Center builds on a tradition of multi-faceted investigation and training in reproductive and women's health at the University of Pennsylvania dating back to 1966. It is an integral part of Penn's exceptional biomedical research enterprise, ranking among the top in the nation in terms of NIH grant awards to medical schools. The short term goals of the WRHR Center are to identify especially talented physicians who have demonstrated potential for successful careers in research, to place them in an exciting and supportive research environment under the guidance of an experienced mentor(s), and to advance their skill sets in research to the point that they can establish a productive, independent line of investigation. Based on successes in the previous funding periods, the Penn WRHR Center will continue to formulate individualized curricula and career development plans. This may include enrollment in a Master of Science or Ph.D. degree program. Academic enrichment including seminars and specialized workshops has been established to enhance research skills as well as publication and grant writing. Continued support for a Biostatistician (instead of a Biostatistics Core) is requested based on its significant contributions to the research career development of Scholars during the past periods of support. The long term goals of the Center are to insure that Scholars who graduate from the Penn WRHR Center establish sustainable research programs, and develop expertise in mentorship that will allow them to guide future Scholars. A novel feature of the present proposal is that we have incorporated the joint recruitment of WRHR Scholars with Temple University (non-research intensive department of Ob/Gyn) and Howard University (minority institution) in order to start building the Women's Health Research manpower at those institutions. Overall success of the Penn WRHR Center will be measured in terms of the quality and importance of work published by the Scholars, their ability to win and retain extramural research funding, professional recognition for their research activities, effectiveness in mentoring trainees under their direction, academic promotion, and assumption of leadership roles in the specialty of Obstetrics and Gynecology.

Public Health Relevance

The Penn WRHR Center will encourage and foster the development of academic obstetrician gynecologists in order to contribute to the improvement of the health of women and their children.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Physician Scientist Award (Program) (PSA) (K12)
Project #
Application #
Study Section
Special Emphasis Panel (ZHD1-DSR-L (14))
Program Officer
Parrott, Estella C
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Pennsylvania
Obstetrics & Gynecology
Schools of Medicine
United States
Zip Code
Levine, Lisa D; Downes, Katheryne L; Elovitz, Michal A et al. (2016) Mechanical and Pharmacologic Methods of Labor Induction: A Randomized Controlled Trial. Obstet Gynecol 128:1357-1364
Edelson, P Kaitlyn; Bastek, Jamie A; Levine, Lisa D (2016) Evaluating the Obstetrical Implications of Antenatal Testing for Women with Morbid Obesity: Maternal and Fetal Outcomes of Increased Surveillance. Am J Perinatol 33:839-43
Levine, Lisa D; Schulkin, Jay; Mercer, Brian M et al. (2016) Role of the Hospitalist and Maternal Fetal Medicine Physician in Obstetrical Inpatient Care. Am J Perinatol 33:123-9
Senapati, Suneeta; Sammel, Mary D; Morse, Christopher et al. (2016) Impact of endometriosis on in vitro fertilization outcomes: an evaluation of the Society for Assisted Reproductive Technologies Database. Fertil Steril 106:164-171.e1
Turitz, Amy L; Bastek, Jamie A; Purisch, Stephanie E et al. (2016) Patient characteristics associated with 17-alpha hydroxyprogesterone caproate use among a high-risk cohort. Am J Obstet Gynecol 214:536.e1-5
Levine, Lisa D; Srinivas, Sindhu K (2016) Length of second stage of labor and preterm birth in a subsequent pregnancy. Am J Obstet Gynecol 214:535.e1-4
Bastek, Jamie A; Sammel, Mary D; Jackson, Tara D et al. (2015) Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA. Am J Obstet Gynecol 212:236.e1-10
O'Neill, Kathleen E; Senapati, Suneeta; Dokras, Anuja (2015) Use of gonadotropin-releasing hormone agonist trigger during in vitro fertilization is associated with similar endocrine profiles and oocyte measures in women with and without polycystic ovary syndrome. Fertil Steril 103:264-9
Levine, Lisa D; Gonzales, Gustavo F; Tapia, Vilma L et al. (2015) Preterm birth risk at high altitude in Peru. Am J Obstet Gynecol 212:210.e1-8
Levine, Lisa D; Sammel, Mary D; Hirshberg, Adi et al. (2015) Does stage of labor at time of cesarean delivery affect risk of subsequent preterm birth? Am J Obstet Gynecol 212:360.e1-7

Showing the most recent 10 out of 31 publications