This application is the 3rd competing renewal for the Colorado Women's Reproductive Health Research career development program, established in 1999. Over the past 15 years, we have trained 11 scholars, all of whom have remained in academic medicine and who collectively have produced over 200 publications. In our third cycle, we added excellence in clinical research to a strong basic science base and plan to continue to develop opportunities for clinical and translational science, as well as team science, by increasing the breadth of our mentor pools and strengthening our collaborations with the Center for Women's Health Research and the Colorado Clinical and Translational Sciences Institute's Child and Maternal Health Program.
Our specific aims are to: 1) Support 2-3 top applicants who have completed a residency in Obstetrics and Gynecology from a national pool of exceptionally motivated and talented individuals, and provide them with an appropriately tailored, top-quality mentored research experience; 2) Expand our flexible program of training and support for junior faculty physician scientists to include individuals with diverse backgrounds, both in training and life experience, and expose them to the principles of team science and interdisciplinary research and provide support for up to 5 years; 3) Provide scholars with outstanding mentors from within and without the department of Ob/Gyn, including expertise in Endocrinology, Epidemiology, Immunology, Neonatology, Oncology, Pediatrics, and Psychiatry, among others, all of whom are senior scientists with track records of funding and training; 4) Maintain and expand our well-developed core statistical resources to enable scholars to address the widest possible variety of research questions in ongoing collaborations; and 5) Complete the transformation of the institutional and departmental culture to nurture team science incubators poised to address key research problems in women's reproductive health. Our Internal Program Advisory Committee will continue to provide program support and evaluation, and we shall establish an External Program Advisory Committee in the present proposal to assure that we stay abreast of national trends in Ob/Gyn research.

Public Health Relevance

Academic research in Obstetrics and Gynecology has long suffered from an inadequate cadre of investigators with top quality training, sufficient to make them competitive for limited research funding dollars. By training the research leaders of tomorrow to address the most important, pressing questions in women's reproductive health, and equipping them to find the answers, we have every expectation that this grant will lead to tangible improvements in women's health in the United States.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD001271-18
Application #
9313136
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Halvorson, Lisa M
Project Start
2015-07-31
Project End
2020-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
18
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Dickson, Betsy; Mansfield, Chanel; Guiahi, Maryam et al. (2018) Recommendations From Cannabis Dispensaries About First-Trimester Cannabis Use. Obstet Gynecol 131:1031-1038
Wu, Fang; Scroggin, Triniti L; Metz, Torri D et al. (2018) Development of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Simultaneous Determination of Four Cannabinoids in Umbilical Cord Tissue. J Anal Toxicol 42:42-48
Harrison, Margo S; Scarbro, Sharon; Juarez-Colunga, Elizabeth et al. (2018) Trends in the Mode of Delivery of Pregnant Women in Rural Guatemala from a Quality Improvement Database. Matern Child Health J :
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Robison, Elizabeth; Heyborne, Kent; Allshouse, Amanda A et al. (2017) Implementation of a Risk-Based Heparin Protocol for Postpartum Venous Thromboembolism Prevention. Obstet Gynecol 130:262-269
Mak, Winifred; Kondapalli, Laxmi A; Celia, Gerard et al. (2016) Natural cycle IVF reduces the risk of low birthweight infants compared with conventional stimulated IVF. Hum Reprod 31:789-94
Metz, Torri D; Rovner, Polina; Hoffman, M Camille et al. (2016) Maternal Deaths From Suicide and Overdose in Colorado, 2004-2012. Obstet Gynecol 128:1233-1240

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