University of Colorado Anschutz Medical Campus (UCAMC) """"""""Building Interdisciplinary Research Careers in Women's Health"""""""" (Colorado BIRCWH) Program renewal is to provide outstanding junior faculty with state-of-the-art interdisciplinary and individualized career development training that will maximize their ability to establish independent biomedical research careers in areas relevant to improving women's health. Long term, we seek to benefit the field of women's health research and ultimately, women's health, by adding a well-trained, diverse group of researchers to the work force who are equipped to answer key scientific questions about women's health and sex differences. To accomplish these goals we have created an environment that nurtures interdisciplinary collaborations in focused and interactive research areas that are essential to improving the health of women. The Colorado BIRCWH will continue to be housed in the Center for Women's Health Research (CWHR), which provides key programs both on campus and in the community that support our BIRCWH Scholars. In addition, since the 2007 award of the Colorado BIRCWH grant, UCAMC has successfully competed for a Clinical and Translational Science Award from NIH (CCTSI- Colorado Clinical Translational Science Institute). The programs offered by the CCTSI, with which the Colorado BIRCWH has a mutually beneficial affiliation, provide a rich environment for our BIRCWH Scholars in concert with the BIRCWH-specific programs and those of the CWHR. The UCAMC has a very high level of support for the BIRCWH, exemplified by strong financial support from the Dean of the School of Medicine for the BIRCWH. The Leadership Team for the Colorado BIRCWH will be headed by Judith Regensteiner, PhD who will continue as Principal Investigator/Program Director (PI/PD) with Nanette Santoro as coPI/PD. Both have extensive mentoring and research experience. We will select promising and diverse BIRCWH Scholars, as we have over the course of the current project period who will be paired with experienced mentors (and who will have mentor teams) from our multiple campuses and schools in 3 interdisciplinary and interrelated focus areas across the lifespan in which UCAMC has great strength including 1. Pregnancy: placentation, lactation, fetal/neonatal programming, 2. Immunology/Rheumatology/Inflammation and 3. Adult Health: obesity, menopause, aging, diabetes and cardiovascular disease. Scholars will also have access to UCAMC's rich base of institutional research resources including interdisciplinary programs and coursework, as well as substantial core facilities. Because of the complexity of most current research, interdisciplinary research teams are the wave of the future and our BIRCWH Scholars should become extraordinarily well-positioned to be the next generation of leaders in biomedical science. Given the success of our BIRCWH Scholars in the current program we are eager to continue developing and improving our program through this renewal.

Public Health Relevance

The proposed program is relevant to career development of junior faculty in women's health research. Junior faculty who are selected for participation in the program will receive mentoring through by a primary mentor and team mentoring approach as well as access to other resources including biostatistical support, required and optional coursework and a Seminar series. The overall objective of the University of Colorado Anschutz Medical Campus (UCAMC) Building Interdisciplinary Research Careers in Women's Health (Colorado BIRCWH) Program, is to provide outstanding junior faculty with state-of-the-art interdisciplinary and individualized career development training that will maximize their ability t establish independent biomedical research careers in areas relevant to improving women's health.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Physician Scientist Award (Program) (PSA) (K12)
Project #
Application #
Study Section
Special Emphasis Panel ()
Program Officer
Davis Nagel, Joan
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Colorado Denver
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Thompson, Lauren E; Chan, Paul S; Tang, Fengming et al. (2018) Long-Term Survival Trends of Medicare Patients After In-Hospital Cardiac Arrest: Insights from Get With The Guidelines-Resuscitation®. Resuscitation 123:58-64
Yao, Yuan; Johnson, Nicholas James; Perman, Sarah Muirhead et al. (2018) Myocardial dysfunction after out-of-hospital cardiac arrest: predictors and prognostic implications. Intern Emerg Med 13:765-772
Jonker, Sonnet S; Kamna, Daniel; Loturco, Dan et al. (2018) IUGR impairs cardiomyocyte growth and maturation in fetal sheep. J Endocrinol :
Cree-Green, Melanie; Stuppy, Jacob J; Thurston, Jessica et al. (2018) Youth With Type 1 Diabetes Have Adipose, Hepatic, and Peripheral Insulin Resistance. J Clin Endocrinol Metab 103:3647-3657
Zwick, Rachel K; Rudolph, Michael C; Shook, Brett A et al. (2018) Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation. Nat Commun 9:3592
Demoruelle, M Kristen; Bowers, Emily; Lahey, Lauren J et al. (2018) Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis. Arthritis Rheumatol 70:516-527
Bjornstad, Petter; Cree-Green, Melanie; Baumgartner, Amy et al. (2018) Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtform Pediatr Diabetes 19:436-442
Cree-Green, Melanie; Xie, Danielle; Rahat, Haseeb et al. (2018) Oral Glucose Tolerance Test Glucose Peak Time Is Most Predictive of Prediabetes and Hepatic Steatosis in Obese Girls. J Endocr Soc 2:547-562
Rudolph, Michael C; Jackman, Matthew R; Presby, David M et al. (2018) Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance. Diabetes 67:651-661
Simon, Stacey L; Behn, Cecilia Diniz; Cree-Green, Melanie et al. (2018) Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity. J Pediatr :

Showing the most recent 10 out of 114 publications