The overall goal of this application is to establish a new K12 Multidisciplinary Clinical Research Career Development Program (MCRCDP) at Washington University (WU) in collaboration with St. Louis University (SLU). The MCRCDP unites a broad array of scholars from multiple different schools at WU (Medicine, Social Work, Engineering, Arts and Science) and SLU (Public Health, Nursing, Medicine) to improve clinical research training. The MCRCDP will be coordinated with WU's newly awarded K30 Clinical Research Curriculum Program to leverage resources and to foster more integration and multidisciplinary training. The applicant is also establishing ties with less research intensive institutions (St. Louis College of Pharmacy, the University of Missouri-St. Louis School of Nursing, and Southern Illinois University School of Nursing) to train scholars from diverse disciplines in team settings. The goal is to create a new innovative clinical research training program by bringing diverse individuals together into a multidisciplinary advisory committee (MAC), establishing specific functional cores for the program, expanding existing coursework, and developing new courses into a formal didactic curriculum leading to a masters degree in clinical investigation, as well as creating a new dual mentor clinical research practicum for hands-on practical research training. This program will be focused on prompting extensive interaction among scholars, faculty, mentors, and MAC members from multiple diverse disciplines. The MAC, mentors, faculty, and scholars, the curriculum and the research practicum will be regularly evaluated to continuously improve the program. Scholars will be tracked longitudinally to monitor their career development and milestones to measure the success of this training program. The applicant will work closely with the NIH and other K12 multidisciplinary clinical research training programs to identify best practices and to share knowledge and resources to promote team based training. WU and Barnes Jewish Hospital have provided dedicated space and $800,000 to directly support this program as evidence of their institutional commitment to the K12 MCRCDP.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
1K12RR023249-01
Application #
7050278
Study Section
Special Emphasis Panel (ZHD1-MRG-C (16))
Program Officer
Merchant, Carol
Project Start
2005-09-23
Project End
2010-08-31
Budget Start
2005-09-23
Budget End
2006-08-31
Support Year
1
Fiscal Year
2005
Total Cost
$1,540,000
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Theodoro, Daniel; Olsen, Margaret A; Warren, David K et al. (2015) Emergency Department Central Line-associated Bloodstream Infections (CLABSI) Incidence in the Era of Prevention Practices. Acad Emerg Med 22:1048-55
Marschall, J; Lewis, J W S; Warren, D K et al. (2014) Baseline hypovitaminosis D is not associated with poor clinical outcomes in osteoarticular infections. Int J Infect Dis 26:98-102
Theodoro, Daniel; Owens, Pamela L; Olsen, Margaret A et al. (2014) Rates and timing of central venous cannulation among patients with sepsis and respiratory arrest admitted by the emergency department*. Crit Care Med 42:554-64
Lane, Michael A; Zeringue, Angelique; McDonald, Jay R (2014) Serious bleeding events due to warfarin and antibiotic co-prescription in a cohort of veterans. Am J Med 127:657-663.e2
Khair, H N; VanTassell, P; Henderson, J P et al. (2013) Vancomycin resistance has no influence on outcomes of enterococcal bacteriuria. J Hosp Infect 85:183-8
Chen, Li-Shiun; Xian, Hong; Grucza, Richard A et al. (2012) Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes. Drug Alcohol Depend 123 Suppl 1:S42-51
Lane, M A; Devine, S T; McDonald, J R (2012) High-risk antimicrobial prescriptions among ambulatory patients on warfarin. J Clin Pharm Ther 37:157-60
Alexander, Bryan T; Marschall, Jonas; Tibbetts, Robert J et al. (2012) Treatment and clinical outcomes of urinary tract infections caused by KPC-producing Enterobacteriaceae in a retrospective cohort. Clin Ther 34:1314-23
Lane, Michael A; McDonald, Jay R; Zeringue, Angelique L et al. (2011) TNF-? antagonist use and risk of hospitalization for infection in a national cohort of veterans with rheumatoid arthritis. Medicine (Baltimore) 90:139-45
Lipira, Lauren; Jeffe, Donna B; Krauss, Melissa et al. (2010) Evaluation of clinical research training programs using the clinical research appraisal inventory. Clin Transl Sci 3:243-8

Showing the most recent 10 out of 37 publications