My long-term goal in seeking an SDA is to develop a program of research focusing on the treatment of eating disorders, particularly anorexia nervosa. Specifically, I am committed to developing an outpatient clinical research program that would assess the efficacy of various treatment interventions aimed at reducing relapse rates in anorexia nervosa. Although anorexia nervosa has long been recognized as a serious and chronic disorders warranting intervention, the empirical data available to inform treatment decisions are sparse. The proposed SDA is a first step in developing a career plan that would enable me to gain the training and experience necessary to contribute substantially to this limited knowledge base in the field of eating disorders. The primary question addressed by this proposal is whether cognitive- behavioral treatment is an effective post-hospitalization, outpatient therapy as compared with Nutritional Counseling. In addition to receiving medical management of their disorder, 60 women between the ages of 16 and 45 years will be randomly assigned to one of these two outpatient treatment conditions upon discharge from the Eating Disorders Inpatient Unit at NYSPI-Columbia Presbyterian Medical Center. Participants will receive 40 sessions of treatment during a nine month period; primary points of assessment will be: 1) prior to admission to the hospital, 2) at discharge/initiation of the outpatient trial, 3) at termination of treatment; and 4) at 3, 6, and 12 months after completion of the outpatient treatment. Based on results from this study, the subsequent questions of comparative efficacy of psychotherapeutic and psychopharmacological interventions will be pursued.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Scientist Development Award (K21)
Project #
5K21MH001185-05
Application #
2674392
Study Section
Health Behavior and Prevention Review Committee (HBPR)
Project Start
1994-07-15
Project End
2000-06-30
Budget Start
1998-07-15
Budget End
2000-06-30
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Psychiatry
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Wolk, Sara L; Loeb, Katharine L; Walsh, B Timothy (2005) Assessment of patients with anorexia nervosa: interview versus self-report. Int J Eat Disord 37:92-9
Pike, Kathleen M; Walsh, B Timothy; Vitousek, Kelly et al. (2003) Cognitive behavior therapy in the posthospitalization treatment of anorexia nervosa. Am J Psychiatry 160:2046-9
Pike, K M (1998) Long-term course of anorexia nervosa: response, relapse, remission, and recovery. Clin Psychol Rev 18:447-75
Pike, K M; Walsh, B T (1996) Ethnicity and eating disorders: implications for incidence and treatment. Psychopharmacol Bull 32:265-74
Dunlap, J C (1996) Genetics and molecular analysis of circadian rhythms. Annu Rev Genet 30:579-601