Dr. Sarkisian is a board-certified internist with a Certificate of Added Qualification in Geriatric Medicine. Her research focuses on prevention of disability among older adults, in particular the impact of older adults' expectations for aging on their health behaviors. She has strong observational research skills, and now seeks research training in behavioral interventions and clinical trial methodology. As her primary mentor on the proposed Paul B. Beeson Career Development Award in Aging, Dr. David B. Reuben, a national leader in aging research with extensive experience conducting NIA-funded investigations, will supervise Dr. Sarkisian's research training and career development towards becoming an independent investigator and a leader in the field of aging. Along with Dr. Reuben, a multidisciplinary mentoring team including Dr. Carol M. Mangione, a health services researcher with expertise in community-based participatory research, Dr. Thomas Prohaska, a gerontologist with expertise in physical activity interventions, and Dr. Bernard Weiner, a motivational psychologist, will work closely with Dr. Sarkisian while she conducts the proposed research and acquires new skills that will be critical in her future work conducting community-based interventions aimed at decreasing functional decline among older persons at greatest risk. ? ? Because regular physical activity strongly contributes to the health and quality of life of older adults, identifying effective strategies for increasing physical activity levels among older adults is a current national priority. For adults who have exceeded their life-expectancy at birth, i.e. those aged 80 years and greater, however, as yet there exists little to offer in terms of interventions that can successfully raise and sustain physical activity levels. Previously, Dr. Sarkisian and her interdisciplinary team of mentors designed an innovative behavioral intervention to increase walking among adults aged 65 years and greater by raising their expectations for aging. The objective of the proposed mentored ? research program is to tailor this intervention to octogenarians, and then pilot test the modified intervention in a small randomized clinical trial (RCT). Specifically, in Phase I of the proposed research, Dr. Sarkisian will conduct focus groups to identify the outcome expectations for physical activity among octogenarians, and working closely with her mentors, will design a theoretically-based behavioral intervention to match the expectations most highly valued by octogenarians. In Phase II, Dr. Sarkisian will conduct a small RCT of the modified intervention with 60 octogenarians recruited from senior residential facilities to obtain preliminary data that would guide the design of a larger RCT. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
5K23AG024811-03
Application #
7070644
Study Section
Special Emphasis Panel (ZAG1-ZIJ-6 (M1))
Program Officer
Stahl, Sidney M
Project Start
2004-06-15
Project End
2008-05-31
Budget Start
2006-08-01
Budget End
2008-05-31
Support Year
3
Fiscal Year
2006
Total Cost
$208,000
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Gruenewald, Tara L; Seeman, Teresa E; Karlamangla, Arun S et al. (2009) Allostatic load and frailty in older adults. J Am Geriatr Soc 57:1525-31
Sarkisian, Catherine A; Gruenewald, Tara L; John Boscardin, W et al. (2008) Preliminary evidence for subdimensions of geriatric frailty: the MacArthur study of successful aging. J Am Geriatr Soc 56:2292-7
Wong, Mitchell D; Sarkisian, Catherine A; Davis, Cynthia et al. (2007) The association between life chaos, health care use, and health status among HIV-infected persons. J Gen Intern Med 22:1286-91
Sayles, Jennifer N; Ryan, Gery W; Silver, Junell S et al. (2007) Experiences of social stigma and implications for healthcare among a diverse population of HIV positive adults. J Urban Health 84:814-28
Sarkisian, Catherine A; Prohaska, Thomas R; Davis, Connie et al. (2007) Pilot test of an attribution retraining intervention to raise walking levels in sedentary older adults. J Am Geriatr Soc 55:1842-6
Sarkisian, Catherine A; Shunkwiler, Sara M; Aguilar, Iris et al. (2006) Ethnic differences in expectations for aging among older adults. J Am Geriatr Soc 54:1277-82
Sarkisian, Catherine A; Prohaska, Thomas R; Wong, Mitchell D et al. (2005) The relationship between expectations for aging and physical activity among older adults. J Gen Intern Med 20:911-5