I am a physician and early career translational investigator, with a research focus on identifying effective approaches for integrating substance abuse treatment into general healthcare settings. Because screening patients for substance abuse is time consuming on the part of clinicians, I propose research to address the validity of patient self-administered screening. The specific research and training aims of this study are integrated around two primary areas of focus: behavioral research methods (survey research, quantitative analysis, qualitative methods) and implementation research. Each of these areas is anchored by an experienced mentor with corresponding expertise, and further developed through didactic instruction combining coursework and directed readings as well as research experience. Under the sponsorship of my primary mentor Marc Gourevitch, MD, MPH, my research and training plans utilize the clinical and academic resources of New York University-Langone Medical Center and Bellevue Hospital, where substance abuse treatment and research has been a longstanding area of emphasis. My proposed study explores an innovative approach to improving rates of substance use screening in primary care, a major impediment to which has been the lack of a brief instrument that can accurately and efficiently identify patients with unhealthy substance use behaviors. The widely accepted and validated """"""""Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) is too lengthy for the typical medical visit, and greatly under-utilized as a result. I will adapt the ASSIST, which was designed and validated to be administered as an in-person interview, to an audio guided computer-assisted self interview (ACASI) that patients can complete prior to their medical visit. I plan a mixed methods study in 3 phases to 1) adapt the ASSIST for ACASI administration in an urban safety- net primary care clinic population;2) test its validity relative to the traditional interviewer-administered ASSIST;and 3) explore physician attitudes to using these screening results to address substance use in the primary care office.

Public Health Relevance

The proposed study will make a valuable contribution to advancing the integration of substance use screening into regular primary care practice. This is an important step toward my long-term goal of developing, implementing, and disseminating simple but effective interventions that improve the capacity of medical systems to respond to the health burden of substance abuse and dependence. My research, mentorship and training activities lay the groundwork for a line of research that will define my career as an independent investigator and physician leader in improving the health of substance users.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Mentored Patient-Oriented Research Career Development Award (K23)
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Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Denisco, Richard A
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New York University
Internal Medicine/Medicine
Schools of Medicine
New York
United States
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Kumar, Pritika C; Cleland, Charles M; Gourevitch, Marc N et al. (2016) Accuracy of the Audio Computer Assisted Self Interview version of the Alcohol, Smoking and Substance Involvement Screening Test (ACASI ASSIST) for identifying unhealthy substance use and substance use disorders in primary care patients. Drug Alcohol Depend 165:38-44
Spear, Suzanne E; Shedlin, Michele; Gilberti, Brian et al. (2016) Feasibility and acceptability of an audio computer-assisted self-interview version of the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in primary care patients. Subst Abus 37:299-305
McNeely, Jennifer; Strauss, Shiela M; Rotrosen, John et al. (2016) Validation of an audio computer-assisted self-interview (ACASI) version of the alcohol, smoking and substance involvement screening test (ASSIST) in primary care patients. Addiction 111:233-44
McNeely, Jennifer; Strauss, Shiela M; Saitz, Richard et al. (2015) A Brief Patient Self-administered Substance Use Screening Tool for Primary Care: Two-site Validation Study of the Substance Use Brief Screen (SUBS). Am J Med 128:784.e9-19
McNeely, Jennifer; Saitz, Richard (2015) Appropriate Screening for Substance Use vs Disorder. JAMA Intern Med 175:1997-8
McNeely, Jennifer; Cleland, Charles M; Strauss, Shiela M et al. (2015) Validation of Self-Administered Single-Item Screening Questions (SISQs) for Unhealthy Alcohol and Drug Use in Primary Care Patients. J Gen Intern Med 30:1757-64
McNeely, Jennifer; Halkitis, Perry N; Horton, Ariana et al. (2014) How patients understand the term ""nonmedical use"" of prescription drugs: insights from cognitive interviews. Subst Abus 35:12-20
McNeely, Jennifer; Strauss, Shiela M; Wright, Shana et al. (2014) Test-retest reliability of a self-administered Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in primary care patients. J Subst Abuse Treat 47:93-101
Lee, Joshua D; McNeely, Jennifer; Grossman, Ellie et al. (2014) Clinical case conference: unobserved ""home"" induction onto buprenorphine. J Addict Med 8:309-14
McNeely, Jennifer; Wright, Shana; Matthews, Abigail G et al. (2013) Substance-use screening and interventions in dental practices: survey of practice-based research network dentists regarding current practices, policies and barriers. J Am Dent Assoc 144:627-38

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