Smoking is the leading cause of preventable death and disability in the U.S., and is becoming increasingly concentrated among individuals with low socioeconomic status (SES) and racial/ethnic minorities. Nearly half of U.S. adults have difficulties with health literacy (HL), and lack the ability to obtain, understand, and use basic health information to make important decisions about healthcare. As with smoking, low HL is common among racial/ethnic minorities and those with low SES. Low HL is associated with negative health behaviors, less engagement in preventive services, and poor health outcomes. It is also associated with current smoking, key established predictors of smoking relapse, and smoking relapse, even after controlling for sociodemographic indicators. Thus, low HL appears to be an independent risk factor for poor cessation outcomes among low- SES, racially/ethnically diverse smokers. Efforts are needed to elucidate mechanisms of the association between low HL and relapse, and to develop smoking cessation interventions targeting low HL smokers. This project aims to: 1) investigate mechanisms through which HL influences smoking cessation in low- SES, racially/ethnically diverse smokers enrolled in cessation treatment using secondary analyses of traditional questionnaire and ecological momentary assessment (EMA) data from 2 smoking cessation treatment studies; 2) conduct a qualitative investigation with low HL smokers to further elucidate mechanisms of the association between HL and cessation and inform the development of a theoretically-based, cessation treatment targeting the specific needs of low HL smokers; 3) develop and evaluate the preliminary efficacy of a smoking cessation intervention targeting low HL smokers compared to standard treatment; and 4) examine treatment effects on secondary outcomes of interest (e.g., differential dropout, treatment satisfaction, intention to quit smoking). Results will elucidate the complex relations between HL and cessation in underserved smokers, guide treatment for low HL smokers, and contribute to reducing tobacco-related health disparities. Diana Stewart Hoover, Ph.D. is seeking 5 years of support through a NIDA K23 Career Development Award for the proposed training and research. In order to fill critical gaps in her experience, she will obtain specialized training in behavioral intervention development targeting underserved populations, advanced statistics for analyzing longitudinal and EMA data, and qualitative methods, particularly mixed methods. She will also expand her knowledge and skills related to HL, tobacco cessation, health disparities, and research ethics. Her training and research plans will support her long-term goal of establishing an independently-funded research program in cancer prevention and tobacco cessation, with a focus on reducing tobacco-related health disparities for individuals with low HL. A comprehensive training plan is described, combining mentored research, structured mentorship activities guided by established researchers in the field, formal coursework and workshops, and participation in seminars at the University of Texas MD Anderson Cancer Center.

Public Health Relevance

/RELEVANCE Nearly half of United States adults have difficulty with health literacy, defined as 'the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions.' Individuals with health literacy difficulties are more likely to be current smokers and to have less knowledge about smoking health risks and more trouble quitting smoking, putting them at risk for poor health (e.g., more frequent diagnoses of advanced stage cancer) and premature mortality. Efforts are needed to understand mechanisms through which health literacy influences smoking cessation in order to help identify treatment targets for smokers with health literacy difficulties, improve current smoking cessation interventions, and ultimately reduce the burden of tobacco-related health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
1K23DA040933-01A1
Application #
9170878
Study Section
Special Emphasis Panel (ZRG1-HDM-Y (56))
Program Officer
Aklin, Will
Project Start
2016-09-01
Project End
2021-08-31
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
1
Fiscal Year
2016
Total Cost
$166,280
Indirect Cost
$12,317
Name
University of Texas MD Anderson Cancer Center
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
800772139
City
Houston
State
TX
Country
United States
Zip Code
77030
Pappadis, Monique R; Volk, Robert J; Krishnan, Shilpa et al. (2018) Perceptions of overdetection of breast cancer among women 70 years of age and older in the USA: a mixed-methods analysis. BMJ Open 8:e022138
Housten, Ashley J; Lowenstein, Lisa M; Hoover, Diana S et al. (2018) Limitations of the S-TOFHLA in measuring poor numeracy: a cross-sectional study. BMC Public Health 18:405
Housten, Ashley J; Pappadis, Monique R; Krishnan, Shilpa et al. (2018) Resistance to discontinuing breast cancer screening in older women: A qualitative study. Psychooncology 27:1635-1641
Hoover, Diana S; Pappadis, Monique R; Housten, Ashley J et al. (2018) Preferences for Communicating about Breast Cancer Screening Among Racially/Ethnically Diverse Older Women. Health Commun :1-5
Hoover, Diana Stewart; Wetter, David W; Vidrine, Damon J et al. (2018) Enhancing Smoking Risk Communications: The Influence of Health Literacy and Message Content. Ann Behav Med 52:204-215
Spears, Claire Adams; Hedeker, Donald; Li, Liang et al. (2017) Mechanisms underlying mindfulness-based addiction treatment versus cognitive behavioral therapy and usual care for smoking cessation. J Consult Clin Psychol 85:1029-1040
Vinci, Christine; Guo, Lin; Spears, Claire A et al. (2017) Socioeconomic indicators as predictors of smoking cessation among Spanish-Speaking Mexican Americans. Ethn Health :1-13
Spears, Claire Adams; Houchins, Sean C; Bamatter, Wendy P et al. (2017) Perceptions of Mindfulness in a Low-income, Primarily African American Treatment-Seeking Sample. Mindfulness (N Y) 8:1532-1543
Vinci, Christine; Li, Liang; Wu, Cai et al. (2017) The association of positive emotion and first smoking lapse: An ecological momentary assessment study. Health Psychol 36:1038-1046